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311株肺炎克雷伯菌感染分布及耐药分析 被引量:16

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摘要 目的分析2014年至2015年本院分离的311株肺炎克雷伯菌的分布及耐药性,为临床控制感染和合理用药提供依据。方法采用DADE BEHRING Micro Scan A/S-4微生物鉴定药敏系统对311株肺炎克雷伯菌进行细菌鉴定和药敏试验,使用WHONET5.4软件进行统计分析。结果 311株肺炎克雷伯菌感染中,男性比女性多,感染率最高的是〉60岁老年人群(46.3%),儿童感染以0-1月新生儿最多(9.3%)。科室分布以ICU(25.7%)、呼吸内科(10.9%)、新生儿科(9.3%)、神经外科(8.0%)为主。痰液标本检出率(57.2%)最高。产ESBLs菌株阳性率为34.7%,其对氨曲南、青霉素类和头孢菌素类耐药率(除头孢西丁外)均超过了88.9%,ESBLs阴性菌株耐药率较高的有氨苄青霉素80.3%和哌拉西林51.2%。结论肺炎克雷伯菌多发生于ICU病房、老年人及新生儿等免疫力低下的感染患者。产ESBLs肺炎克雷伯菌耐药情况较为严重,临床应加强耐药性监测。
出处 《实验与检验医学》 CAS 2016年第3期375-376,共2页 Experimental and Laboratory Medicine
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