摘要
目的分析某综合性医院急性中毒患者的临床及流行病学特点，为今后急性中毒防治提供参考依据。方法回顾性分析2009年7月至2015年5月温州医科大学附属第一医院急诊医学中心收治的660例急性中毒患者的临床资料。结果660例急性中毒患者中男性多于女性（男女比1．36：1）；中毒高发年龄为≥30岁（78．79％）；职业分布中农民最多（39．70％）；以生活性中毒为主（88．18％），自杀是其主要原因（62．42％），以女性多见；毒物种类以农药为主（67．58％），多为中重度中毒（81．82％）；农药中毒中，有机磷、百草枯居前2位，百草枯中毒的血液净化构成比明显高于其他农药中毒，差异有统计学意义（X2=105．21，P=0．00）；有212例中毒患者并发脏器功能障碍，以农药中毒多见，而在农药中毒中尤以百草枯中毒的构成比最大，差异有统计学意义（x2=45．09，P=0．00）；急性中毒病死率2．27％，百草枯中毒死亡和放弃治疗出院构成比明显高于其他所有农药中毒（X2=56．83，P=0．00）。结论农药中毒仍是综合性医院急性中毒研究重点（尤其有机磷、百草枯中毒），且多为中重度中毒。
Objective To analyze the clinical and epidemiological characteristics of acute poisoning patients in a general hospital, then to provide a reference for the prevention and treatment of acute poisoning in the future. Methods A retrospective analysis was made on the clinical data of 660 patients with acute poisoning admitted in emergency medical center of the First Affiliated Hospital of Wenzhou Medical University from July 2009 to May 2015. Results More men than women in 660 cases with acute poisoning（the ratio of male to female was 1.36：1 ） ; ≥ 30 years old was the high incidence age （78.79%） ;The top occupation was farmers （39.70%） ; Most were life poisoning （88.18%）, suicide was the main reason （62.42%） especially happened in women, and the main cause of suicide was family conflicts ;Toxic species dominated by pesticide （67.58%）, most were severe poisoning （81.82%） ; The top two pesticide poisoning were organic phosphorus and paraquat,and the proportion of blood purification in paraquat was significantly higher（x2=105.21 ,P=0.00） ;There were 212 cases with organ dysfunction,main were pesticide poisoning patients,and the proportionof organ dysfunction in paraquat was significantly higher than the rest allpesticide poisoning （X2=45.09,P=0.00） ;The general fatal rate of acute poisoning was 2.27%, and the proportion in paraquat poisoning was .higher than the rest pesticide poisoning who were death and give up when discharged （X2=56.83,P=0.00）. Conclusion The focus of acute poisoning in the general hospital is still pesticide （especially organic phosphorus and paraquat）, and most were severe poisoning.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
2016年第7期506-509,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
基金
项目资助：浙江省医学创新学科建设计划（11-CX26）
浙江省中医药重点学科计划（2012-XK.A28）
浙江省“十二五”重点学科建设项目（2012-207）
关键词
中毒
急性
诊断相关患者组
流行病学研究
Poisoning, acute
Diagnosis-related groups
Epidemiology studies
