摘要
目的探讨血清降钙素原(PCT)对腰大池置管持续引流治疗颅内感染的效果评价。方法选取我院31例开颅术后并发感染的患者,根据治疗效果将患者分为治愈组和有效组,应用腰大池置管持续引流术结合鞘内注射药物治疗颅内感染并监测患者血清PCT水平。结果经过治疗后治愈率为87.10%;治愈组患者与有效组患者在置管前、置管后1d、3d时PCT水平间比较差异无统计学意义(P>0.05);置管后第5天治愈组患者PCT水平明显低于有效组患者,且组间比较差异有统计学意义(P<0.05);出院前1d治愈组患者PCT水平低于有效组患者,但是差异无统计学意义(P>0.05);治愈组患者中置管第5天及出院前1d血清PCT水平分别与置管后第1天相比,差异均有统计学意义(P<0.05)。结论腰大池置管持续引流治疗颅内感染效果确切,PCT水平可作为感染控制的评价指标之一。
Objective To investigate the effect of serum calcitonin （PCT） on the treatment of intracranial infection by continuous drainage of lumbar cistern. Method We selected 31 cases of concurrent infection after craniotomy. Based on the treatment effect patients were divided into cure group and effective group. The drainage tube was placed in lumbar cistern combined with intrathecal drug. Serum PCT level was monitored. Result After treatment, the cure rate was 87.10%. PCT content had no statistical difference between cure group and effective group at 1D, 3D of catheter placement （P 〉 0.05）. PCT level was significantly lower in cure group at 5D of catheter placement （P 〈 0.05）. PCT levels in cure patients were lower than the effective group 1 say before discharge, but the difference was not statistically significant （P 〉 0.05）. with mid pipe 5D and discharged 1 day before The serum PCT level in cure group patients was statistically different when compared 1st day post catheter with 5 day post catheter and 1 day before discharge （P 〈 0.05）. Conclusion The effect of continuous drainage of lumbar cistern on the treatment of intracranial infection is evident. PCT level can be used as one of the evaluation indicators for infection control.
出处
《标记免疫分析与临床》
CAS
2016年第7期802-804,共3页
Labeled Immunoassays and Clinical Medicine
关键词
降钙素原
腰大池置管持续引流
开颅术
颅内感染
Calcitonin
Continuous drainage of lumbar cistern drainage
Craniotomy
Intracranial infection
