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2型糖尿病肾病患者肾功能、糖化血红蛋白、尿微量白蛋白与血脂代谢的相关性 被引量:8

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摘要 目的分析2型糖尿病肾病患者肾功能、糖化血红蛋白、尿微量白蛋白与血脂代谢的相关性,为临床诊断和治疗2型糖尿病肾病提供相关参考。方法选取我院收治的2型糖尿病肾病患者46例为试验组,收集同期于我院进行健康体检的志愿者45例为对照组,其中试验组患者依据尿微量白蛋白排泄率(UAER)分为NAU组(UAER<30 mg/d,n=16)、MAU组(30≤UAER<300 mg/d,n=14)、CAU组(UAER 300 mg/d,n=16),依据糖化血红蛋白水平(Hb A1C)分为I组(Hb A1C<6%,n=15)、II组(6%≤Hb A1C≤8%,n=16)、III组(Hb A1C>8%,n=15),检测并对比各组血清生化指标。结果试验组HDL-C含量低于对照组,BUN、Cr、m Alb、FPG、Hb A1C、LDL-C、TG、TCH指标均高于对照组,差异具有统计学意义(P<0.05);NAU组HDL-C指标高于CAU组和MAU组,FPG、Hb A1C、LDL-C、TG、TCH指标低于CAU组和MAU组,差异具有统计学意义(P<0.05);I组FPG、Hb A1C低于II组和III组,差异具有统计学意义(P<0.05);肾功能指标BUN和Cr、Hb A1C、m Alb与血脂代谢指标LDL-C、TG及TCH均呈正相关,与血脂代谢指标HDL-C呈负相关。结论 2型糖尿病肾病患者UAER越高,HDL-C越低,FPG、Hb A1C、LDL-C、TG、TCH指标越高;2型糖尿病肾病患者Hb A1C水平越高,对肾脏损害越大。
作者 王英杰
出处 《临床医学研究与实践》 2016年第12期19-20,共2页 Clinical Research and Practice
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