摘要
[目的]观察冠脉通联合西药治疗痰瘀痹阻冠心病心绞痛疗效。[方法]使用随机平行对照方法,将92例门诊患者按就诊顺序编号抽签方法简单随机分为两组。对照组46例阿司匹林,口服,0.1g/次,1次/d;消心痛,口服,5mg/次,3次/d;辛伐他汀,口服,10mg/次,1次/d。治疗组46例冠脉通(半夏9g,瓜蒌15g,皂角刺5g,夏枯草、川芎、金银花、红花各10g,煅牡蛎30g,党参、丹参各15g,桃仁、元胡、香附、地龙各10g),1剂/d,水煎两次,每次取汁250m L,共500m L,兑后分早晚两次服;西药治疗同对照组。连续治疗4周为1疗程。观测临床症状、心绞痛发作次数、不良反应。连续治疗2疗程(8周),判定疗效。[结果]心绞痛疗效:治疗组显效28例,有效14例,无效4例,总有效率91.3%;对照组显效16例,有效14例,无效16例,总有效率65.2%;治疗组疗效优于对照组(P<0.01)。中医证候疗效:治疗组显效34例,有效10例,无效2例,总有效率95.6%;对照组显效18例,有效15例,无效13例,总有效率71.7%;治疗组疗效优于对照组(P<0.01)。心电图疗效:治疗组显效29例,有效15例,无效2例,总有效率95.6%;对照组显效15例,有效15例,无效16例,总有效率65.2%;治疗组疗效优于对照组(P<0.01)。[结论]冠脉通联合西药治疗痰瘀痹阻冠心病稳定型劳累性心绞痛疗效满意。
[Objective] Toobserve Guanmaitongdecoction combined with western medicine of Angina Pectoris（Phlegm Stasis-Bizu）. [Methods] Randomized parallel controlled method, The 92 patients in the clinic according to clinic serial number by simple randomized into two groups. The control group 46 cases of aspirin, oral, 0.1 g/time, 1 times/d; isosorbidedinitrate, oral, 5 mg/time, 3 times/d; simvastatin, oral, 10 mg/ times, 1 times/d. Treatment of 46 patients Guanmaitongsoup （Banxia9 g, Gualou 15 g, Zaojiaoci 5 g, Xiakucao, Chuanxiong,Jinyinhua, Honghuan, 10g each, Duanmuli 30 g, Dangshen,Danshen, 15 g each, Taoren, Yuanhu,Xiangfu, Dilong, 10 geach）, 1/d, frying twice, decoction 250 mL, 500 mL, morning and evening hours; western medicine withthe control group. 4weeks for a course of continuous treatment. Observation of clinical symptoms of angina pectorisdisease foci, angina attacks, adverse reactions. Continuous treatment of 2 courses, to determine efficacy. [Results] Angina treatment group 28 cases, effective in 14 cases, 4 cases, the total efficiency of 91.3%. The control group 16cases markedly effective in 14cases, 16 cases, the total efficiency of 65.2% （P 〈0.01）. TCM syndrome treatment group 34cases, effective in 10cases, 2 cases, the total efficiency of 95.6%. The control group 18 cases markedly effective inl5 cases, 13 cases, the total efficiency of 71.7% （P〈0.01）. ECG efficacy of treatment group 29 cases, 15 cases, 2 cases, thetotal efficiency of 95.6%. The control group 15 cases markedly effective in 15 cases, 16 cases, the total efficiencyof 65.2%. Treatment group than the control group （P〈0.01）. [Conclusion] Guanmaitong decoction combined with western medicine of Angina Pectoris （Phlegm Stasis-Bizu）, The treatment of angina pectoris results were satisfactory.
出处
《实用中医内科杂志》
2016年第8期66-68,共3页
Journal of Practical Traditional Chinese Internal Medicine
