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妊娠早期甲状腺功能筛查研究及其临床意义 被引量:4

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摘要 目的探讨妊娠早期甲状腺功能筛查的临床意义。方法抽取2013年12月~2014年12月在本院就诊的586例妊娠早期妇女,按纳入标准将孕妇分为高风险组和对照组,测定两组甲状腺功能,比较两组甲状腺功能异常的患病率。结果高风险组甲状腺功能异常患病率明显高于对照组(χ2=24.081,P〈0.001),其中甲状腺功能减退患病率为1.8%,高于对照组0.8%(χ2=2.441,P=0.118),亚临床甲减患病率为16.8%,高于对照组4.9%(χ2=19.581,P=0.000);而高风险组无论在甲状腺功能亢进患病率还是亚临床甲亢患病率与对照组的差异均无统计学意义(χ2=1.391,P=0.238;χ2=0.393,P=0.531)。高风险组孕妇TPOAb阳性率为40.7%,显著高于低风险组的19.0%,差异具有统计学意义(χ2=15.647,P〈0.001)。结论妊娠早期妇女进行及时有效的甲状腺功能筛查,能减少产妇妊娠并发症的发生,提高新生儿出生质量。
出处 《临床输血与检验》 CAS 2016年第4期356-358,共3页 Journal of Clinical Transfusion and Laboratory Medicine
基金 芜湖市科技计划项目(No.2014hm23)资助
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  • 1王允锋,杨慧霞.妊娠合并甲状腺功能低减患者的临床分析[J].中华妇产科杂志,2007,42(3):157-160. 被引量:38
  • 2Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: fill Endocrine Society Clinical Practice Guideline J Clin Endocrinol Metab, 2007, 9: S1-S47.
  • 3Montoro MN. Management of hypothyroidism during pregnancy. Clin Obstet Gynecol, 1997, 40:65 -80.
  • 4Anna SL, Lynnae KM, Paul PK, et al. Perinatal outcome in hypothyroid pregnancies. Obstetrics and Gynecology, 1993, 81.. 349-352.
  • 5Wolfberg AJ, Lee-Parritz A, Peller A, et al. Obstetric and neonatal outcomes associated with maternal hypothyroid disease. J Matern Fetal Neonatal Med, 2005, 17: 35- 38.
  • 6Pop VJ, Brouwers EP, Vader HL, et al. Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3--year follow--up study. Clin Endocrinol (Oxf), 2003, 59: 282-288.
  • 7Hollowell JG, LaFranchi S, where do we go from here? Smallridge RC, et al. 2004 -Summary of working group discussing on thyroid functions and gestational outcomes. Thyroid, 2005, 15: 72.
  • 8HaddowJE, Palomaki GE, Allan WC, et al. Maternal thyroid deficiency during pregnancy and subsequent neuro- psychological development ofthe child. N EnglJMed, 1999, 341: 549.
  • 9Vulsma T, Gons MH, de Vijlder JJ. Maternal-fetal transfer of thyroxine in congenital hypothyroidism due to a total organification defect or thyroid agenesis. N Engl J Med, 1989,321 : 13-16.
  • 10Haddow JE, Palomaki GE, Allan WC, et al. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N Engl J Med, 1999,341:549-555.

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