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颅脑CT灌注参数定量分析的准确性 被引量:6

Accuracy of quantitative analysis of cerebral CT perfusion parameters
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摘要 目的探讨灌注图像减薄处理前后灌注参数的稳定性。方法连续选取28例接受颅脑CT灌注成像的患者,均采用Cine full 1.0s扫描模式,在50s内连续曝光扫描。按照所得图像是否经过剪薄处理分为两组,一组为未经剪薄处理的原始图像,为A组;另一组将原始图像进行1/2减薄处理,为B组。由2名影像诊断医师在基底节层面同时测量A、B两组灰质区、豆状核区及白质区的灌注参数脑血流量(CBF)、脑血容量(CBV)及平均通过时间(MTT)并进行比较。结果 A组脑灰质区、豆状核区及脑白质区MTT均低于B组,CBF均高于B组,两组间差异有统计学意义(P均<0.05);A、B两组脑灰质区、豆状核区、白质区CBV差异无统计学意义(P均>0.05)。结论不同的颅脑灌注扫描方式得到的灌注参数不同,以MTT及CBF更为显著。 Objective To explore the stability of perfusion parameters by comparing the perfusion parameters between o- riginal images and cutting the half of original images. Methods Totally of 28 cases underwent brain perfusion scan. All pa- tients were scanned with cine scan 1.0 s mode, and were continuous scanning for 50 s. The original images were defined as A group and the group which were cut the half of original images were as B group. The perfusion parameters such as mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV) were measured and compared in the ar- ea of cerebral gray matter, lenticular nucleus and cerebral white matter. Results The MTT were significant lower in A group than B group in the area of cerebral gray matter, lenticular nucleus and cerebral White matter (all P〈0.05) ; the CBF were significant higher in A group than B group in the area of cerebral gray matter, lenticular nucleus and cerebral white matter (all P〈0.05) ; CBV had no statistical significant between A group and B group. Conclusion The different ways of brain perfusion scan would get to different perfusion parameters, especially the MTT and CBF.
出处 《中国介入影像与治疗学》 CSCD 北大核心 2016年第8期477-480,共4页 Chinese Journal of Interventional Imaging and Therapy
基金 唐山市科技计划项目(14130227a)
关键词 体层摄影术 X线计算机 灌注成像 辐射剂量 Tomography, X-ray computed Brain Perfusion imaging Radiation dosage
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