摘要
目的观察采用单唾液酸四己糖神经节苷脂钠对新生儿缺氧缺血性脑病进行早期治疗的临床效果。方法选取2013年1月至2015年12月我院收治的新生儿缺氧缺血性脑病患儿40例,以随机数字表随机均分为治疗组与对照组各20例,对照组患儿给予常规综合治疗,治疗组患儿在此基础上给予单唾液酸四己糖神经节苷脂钠治疗。比较两组的症状恢复时间、治疗效果。结果治疗组的肌张力、意识、吸吮能力及原始反射恢复时间均显著短于对照组,差异有统计学意义(P<0.05);治疗组患儿的有效率为95.00%,显著高于对照组的65.00%,差异有统计学意义(P<0.05)。结论采用单唾液酸四己糖神经节苷脂钠早期治疗新生儿缺氧缺血性脑病,效果显著,可明显改善患儿的临床症状,值得在临床推广应用。
Objective To observe the clinical effect of monosialotetrahexosylganglioside sodium injection in early treatment of neonatal hypoxic-ischemic encephalopathy. Methods A total of 40 cases of neonatal hypoxic-ischemic encephalopathy admitted to our hospital from January 2013 to December 2015 were selected and randomly divided into two groups, with 20 cases in each group. The control group was given standard comprehensive treatment, while the treatment group was given monosialotetrahexosylganglioside sodium injection on the basis of standard comprehensive treatment. The recovery time of symptoms and curative effect were compared between two groups. Results The recovery time of muscle tension, awareness, sucking ability and primitive reflex of treatment group were significantly shorter than those of control group （P〈0.05）. The effective rate of treatment group was 95.00%, significantly higher than 65.00% of control group （P 〈0.05）. Conclusions The application of monosialotetrahexosylganglioside sodium injection in early treatment of neonatal hypoxic-ischemic encephalopathy has significant efficacy. It can obviously improve the clinical symptoms, and is worthy of clinical promotion.
出处
《临床医学工程》
2016年第8期1091-1092,共2页
Clinical Medicine & Engineering
关键词
单唾液酸四己糖神经节苷脂钠
新生儿缺氧缺血性脑病
早期治疗
效果
Monosialotetrahexosylganglioside sodium injection
Neonatal hypoxic-ischemic encephalopathy
Early treatment
Effect
