摘要
目的:探讨中药防治系统性红斑狼疮(SLE)组方规律。方法:建立临床防治SLE方剂文献数据库,采用数据挖掘关联规则对其组方规律进行系统分析。结果:防治SLE常用方剂为犀角地黄汤和六味地黄丸,常用药对为牡丹皮-生地黄和知母-生地黄,常用药组是赤芍-生地黄-牡丹皮。结论:牡丹皮、生地黄、知母、赤芍是SLE的主要用药,为临床开发防治SLE药物组方提供参考。
Objective： To analyze the law that Systemic Lupus Erythematosus（ SLE） treated by Chinese drugs.Method： The database of SLE treated by Chinese medicine was set up,and then used association rules to analyze the prescription compatibility law. Results： The commonly used formula were Xijiao Dihuang decoction and Liuwei Dihuang pill to treat SLE; For herbal groups,the highest occurrence were the combinations of cortex moutan and radix rehmanniae,anemarrhena and radix rehmanniae. Three kinds of herbals were commonly coupled,such as red peony root,radix rehmanniae and cortex moutan. Conclusion： The cortex moutan,radix rehmanniae,anemarrhena and red peony root are the main herbs in the prevention and treatment of SLE,the compatibility rules laid the foundation for herbal medicine selection and prescription design of SLE.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2016年第7期970-972,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
国际科技合作项目(2013DFG31080)-基于靶标发现技术的治疗自身免疫性疾病中药的合作研究
国家中医药管理局中西医临床重点学科
关键词
系统性红斑狼疮
数据挖掘
关联规则
Systemic Lupus Erythematosus
Data Mining
Association Rules
