摘要
目的探讨卵巢交界性肿瘤（BOT）的临床病理特征及影响预后的相关因素。方法选择2005年1月～2012年12月在四川省自贡市第四人民医院治疗的BOT患者77例，根据病理类型不同，分为浆液性卵巢交界性肿瘤（SBOT）组（43例）和黏液性卵巢交界性肿瘤（MBOT）组（34例）。比较两组患者的肿瘤直径、双侧卵巢累及情况、肿瘤单房或多房等病理特征；采用Logistic多因素回归模型进行BOT患者预后影响因素分析。结果SBOT组患者的肿瘤直径[（10．7±5．0）cm]显著小于MBOT组[（18．4±8．6）cm]；SBOT组患者肿瘤发生于双侧卵巢的比例（30．2％）显著高于MBOT组（17．6％）；SBOT组患者单房肿瘤比例（72．1％）显著高于MBOT组（26．5％），差异均有统计学意义（P〈0．05或P〈0．01）。两组患者微浸润、腹膜种植、术前肿瘤标志物、FIGO分期比较，差异均无统计学意义（P〉0．05）。随访期间共发现6例（7．79％）患者复发，未见死亡病例。病理学组织类型、肿瘤最大径、手术方式、术后是否化疗、糖原抗原125（CA125）水平、CA199水平等临床病理因素与肿瘤的复发无关（P〉0．05）；而国际妇产科联盟（FIGO）分期、微浸润、腹膜种植与复发有关（P〈0．01）。Logistic多因素回归分析结果显示，FIGO分期、微浸润、腹膜种植是影响BOT患者预后的危险因素（P〈0．01）。结论FIGO分期、微浸润、腹膜种植与BOT的复发有关，是影响患者预后的危险因素。
Objective To analyze the clinical pathological characteristics and prognosis influencing factors in borderline ovarian tumors. Methods 77 patients with BOT in the Fourth People＇s Hospital of Zigong City from January 2005 to December 2012 were selected and divided into SBOT group （43 cases） and MBOT group （34 cases） according to the different pathological type. The clinical features of tumor diameter, involving of the bilateral ovaries, single room or multi room of the two groups were compared. The prognosis of the patients with BOT were analyzed by Logistic multiple factors regression analysis. Results The tumor diameter of SBOT group [（10.7±5.0） cm] was less than that of MBOT group [（18.4±8.6） cm], the percentage of bilateral tumors in SBOT group （30.2%） was higher than that in MBOT group （17.6%）, the percentage of single room tumor in SBOT group （72.1%） was higher than that in MBOT group （26.5%）, the differences were all statistically significant （P 〈 0.05 or P 〈 0.01）. Differences of micro-invasion, peritoneal implanta- tion, preoperative tumor markers, FIGO international stages between the two groups were not statistically significant （P 〉 0.05）. 6 cases （7.79%） of tumor recurrences were found, and no death case. There was no relationship was found be- tween tumor recurrences and the pathological type, tumor size, surgical procedure, postoperative chemotherapy, CA125, CA199 （P 〉 0.05）, while the tumor recurrence was related to FIGO stages, micro-invasion, peritoneal implantation （P 〈 0.05）. Logistic multiple factors regression analysis showed that, the FIGO stages, micro-invasion, peritoneal implanta- tion were the risk factors of the prognosis of patients with BOT （P 〈 0.01）. Conclusion The tumor recurrence is related to FIGO stages, micro-invasi0n, peritoneal implantation, the FIGO stages, micro-invasion, peritoneal implantation are the risk factors of the prognosis of patients with BOT.
出处
《中国医药导报》
CAS
2016年第21期123-126,共4页
China Medical Herald
关键词
卵巢交界性肿瘤
影响因素
预后
Borderline ovarian tumors
Influence factor
Prognosis
