摘要
目的通过对比分析阿奇霉素治疗前、后支原体肺炎患儿C-反应蛋白及心肌酶水平,探讨阿奇霉素在治疗小儿支原体肺炎中的疗效。方法以133例支原体肺炎患儿为研究对象,分为对照组66例和研究组67例。对照组采用常规的红霉素治疗,研究组采用阿奇霉素治疗,对比分析两组的治疗效果。结果研究组治疗有效率97.01%显著高于对照组83.33%,差异有统计学意义(P<0.05);两组在接受治疗后C-反应蛋白含量都下降显著,与治疗前比较差异有统计学意义(P<0.05);且研究组C-反应蛋白含量(6.6±0.8)mg/L显著低于对照组(16.2±1.1)mg/L,差异有统计学意义(P<0.05);两组在治疗后心肌酶谱各指标均下降显著,且与治疗前比较差异有统计学意义(P<0.05)。结论在治疗小儿支原体肺炎时阿奇霉素疗效显著,且可有效降低C-反应蛋白及心肌酶含量,减少支原体属感染后对心肌的损伤。
Objective To explore the curative effect of azithromycin in treatment of mycoplasma pneumonia in children by comparing and analyzing the levels of C-reactive protein （CRP） and myocardial enzymes in children with mycoplasma pneumonia before and after azithromycin treatment. Methods A total of 133 children with mycoplasma pneumonia were selected and divided into control group （66 cases） and study group （67 cases） . The children in control group were treated by erythromycin, while the children in study group were treated by azithromycin. The curative effects in the two groups were compared and analyzed. Results The effective rate in study group was 97. 01%, which was statistically significantly higher than that in control group （83.33 % ） （P〈0. 05） ; after treatment, the levels of CRP in the two groups decreased significantly, compared with before treatment, there was statistically significant difference （P〈0. 05） ; the content of CRP in study group was （6. 6±0. 8） rag/L, which was statistically significantly lower than that in control group [ （ 16. 2±1.1 ） mg/L] （P〈0.05） . The levels of myocardial enzymes after treatment in the two groups decreased significantly, compared with before treatment, there was statistically significant difference （P〈0. 05） . Conclusion The curative effect of azithromycin in treatment of mycoplasma pneumonia in children is significant, azithromycin can effectively reduce the contents of CRP and myocardial enzymes and relieve myocardial injury induced by Mycoplasma infection.
出处
《中国妇幼保健》
CAS
2016年第15期3061-3063,共3页
Maternal and Child Health Care of China
关键词
支原体肺炎
阿奇霉素
心肌酶
C-反应蛋白
Mycoplasma pneumonia
Azithromycin
Myocardial enzyme
C-reactive protein
