摘要
目的:观察刮痧联合清心滋肾汤与单纯清心滋肾汤对比治疗围绝经期综合征阴虚火旺证的疗效差异。方法:将80例患者随机分为观察组和对照组,每组40例。对照组仅口服中药清心滋肾汤,每日1剂,分两次服用。观察组在对照组的基础上加用刮痧治疗,主要刮拭足太阳膀胱经、手少阴心经、足少阴肾经循行部位,重点刮拭五脏俞、神门、涌泉、太溪、照海、三阴交、足三里等穴,每周治疗1次。两组均4周为一疗程,连续治疗2个疗程。比较两组治疗前后改良Kupperman评分、围绝经期生存质量量表评分(MENQOL)、血清激素水平[雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)]及临床疗效。结果:除对照组性交痛分项外,两组治疗后改良Kupperman各分项和总分均明显下降(P<0.01,P<0.05),观察组治疗后在潮热汗出、感觉异常、抑郁、疲劳、肌肉关节痛、心悸、蚁爬感、泌尿系症状评分及总分方面改善均优于对照组(P<0.01,P<0.05);两组患者治疗后MENQOL总分及各维度评分较治疗前均明显降低(均P<0.01),观察组在血管舒缩症状、心理状态和生理状态维度评分均低于对照组(P<0.01,P<0.05);两组治疗前后血清激素水平比较差异均无统计学意义(均P>0.05),但观察组治疗后E2有上升趋势,FSH、LH有下降趋势;观察组总有效率为97.4%(37/38),明显高于对照组的81.1%(30/37,P<0.01)。结论:刮痧联合清心滋肾汤及单纯中药治疗均能改善围绝经期综合征患者的症状,提高其生活质量,缓解卵巢衰退的过程,且刮痧联合清心滋肾汤治疗围绝经期综合征疗效优于单纯口服中药。
Objective To observe the efficacy difference between scrapping therapy combined with Qingxin Zishen Decoction and the single application of Qingxin Zishen Decoction for perimenopausal syndrome（PMS）with pattern of fire excess fromyindeficiency.Methods Eighty patients were assinged into an observation group and a control group,40 cases in each one.Patients in the control group were treated with oral administration of Qingxin Zishen Decoction to clear heart heat and nourish kidney.One dose of the decoction was taken by two times within one day.Based on the treatment of the control group,patients in the observation group were additionally treated with scrapping therapy along the urinary bladder meridian of foot-taiyang,heart meridian of hand-shaoyin and kidney meridian of foot-shaoyin;the scrapping therapy was performed at Back-shu points,Shenmen（HT 7）,Yongquan（KI 1）,Taixi（KI 3）,Zhaohai（KI 6）,Sanyinjiao（SP 6）,Zusanli（ST 36）,etc.;the treatment was given once every week.Four weeks of treatment were taken as one course in two groups,and totally 2courses were given.The modified Kupperman score,menopausal quality of life（MENQOL）,level of serum estrogen（E2）,follicle stimulating hormone（FSH）and luteinizing hormone（LH）before and after treatment as well as the clinical efficacy were valuated between the two groups.Results After treatment,each item score and total score of modified Kupperman were reduced apparently in the two groups（P〈0.01,P〈0.05）except dyspareunia score in the control group.The score of hot flash and sweating,paresthesia,depression,fatigue,arthralgia,palpitation,formication,urinary symptoms and total score in the observation group were superior to those in the control group（P〈0.01,P〈0.05）.After treatment,the total score and each dimension score of MENQOL were obviously decreased in the two groups（all P〈0.01）,and the scores of vasomotor symptoms,psychosocial condition and physical condition in the observation group were significantly lower than those in the control group（P〈0.01,P〈0.05）.There were no significant differences of serum hormone levels before and after treatment between the two groups（all P〈0.05）,however,after treatment,the serum E2 level had the tendency to raise and serum LH,FSH levels had the tendency to decrease in the observation group.The total effective rate was 97.4%（37/38）in the observation group,which was higher apparently than 81.1%（30/37）in the control group（P〈0.01）.Conclusion The scrapping therapy combined with Qingxin Zishen Decoction or the simple application of Qingxin Zishen Decoction can both improve PMS symptoms and the quality of life,delay the ovary recession;the combination of scrapping therapy and Qingxin Zishen Decoction achieve superior efficacy on PMS syndrome to the simple application of Qingxin Zishen Decoction.
出处
《中国针灸》
CAS
CSCD
北大核心
2016年第8期821-826,共6页
Chinese Acupuncture & Moxibustion
基金
江苏省中医院科技项目:Y14010
关键词
围绝经期综合征
刮痧
中药
清心滋肾汤
perimenopausal syndrome（PMS）
scrapping therapy
Chinese herbal medicine
Qingxin Zishen Decoction
