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视神经脊髓炎谱系疾病单克隆抗体治疗新进展 被引量:8

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摘要 视神经脊髓炎谱系疾病(neuromyelitis optica spectrum disorders,NMOSD)具有临床反复发作及发作后残疾叠加的特点,减少复发是NMOSD治疗的重点。在NMOSD免疫治疗策略选择中,与常规免疫抑制剂相比,生物制剂具有治疗高度选择性、起效快、长期副作用少等优点,目前单克隆抗体是治疗NMOSD最常用的生物制剂。不同单克隆抗体治疗NMOSD的靶点不同,疗效也有差异。探讨单克隆抗体在NMOSD治疗中的进展,有助于指导其在临床中的应用。基于此,本文对单克隆抗体在NMOSD治疗中的最新进展进行综述。
作者 李静 邱伟
出处 《中国神经免疫学和神经病学杂志》 CAS 2016年第4期277-280,共4页 Chinese Journal of Neuroimmunology and Neurology
基金 国家自然科学基金资助项目(81471218)
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