脉搏灌注变异指数在儿童脓毒症液体复苏中的评价意义被引量：3

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摘要目的探讨脉搏灌注变异指数(PVI)在儿童脓毒症液体复苏中的检测指导价值。方法 69例脓毒症患儿,行早期目标导向治疗(EGDT)后,根据脓毒症休克指南推荐6 h液体复苏的标准将69例患儿分为复苏达标组(35例)和未达标组(34例),比较两组EGDT 3、6 h时PVI的差异;计算复苏达标组3 h PVI的均数,根据该均数将69例患儿分为灌注改善组(46例)和未改善组(23例),比较两组治疗3、6 h乳酸清除率的差异。观察69例患儿入儿童重症监护病房(PICU)时以及治疗后第1、3、6小时的PVI值,监测患儿心率、血压、中心静脉血氧饱和度(Scv O2)、中心静脉压(CVP)等指标。结果复苏达标组在液体复苏3、6 h时PVI值均明显低于未达标组(P<0.05)。治疗6 h时灌注改善组乳酸清除率高于未改善组(P<0.05)。相关性分析结果显示,PVI与CVP和Scv O2呈负相关(r=-0.318、-0.719,P<0.05),与心率和血压无相关性。结论 PVI能够指导儿童脓毒症的容量复苏,具有操作简单、持续无创监测的特点,可对任何疾病患儿进行监测和容量状态评价。

作者李俊燕

机构地区山东省菏泽市立医院儿科

出处《中国实用医药》 2016年第16期37-39,共3页 China Practical Medicine

关键词脉搏灌注变异指数脓毒症儿童液体复苏评价意义

分类号 R720.597 [医药卫生—急诊医学]

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