摘要
目的研究视神经炎在多焦视觉诱发电位(mfVEP)检查中按照不同离心度分布的各同心环的波形特征;追踪视神经炎发病后局部视神经损害情况及经治疗后的恢复情况,从而为视神经炎的诊断、疗效判定及预后监测提供客观依据。方法对30例(30只眼)单眼患轴性球后视神经炎患者进行多焦视觉诱发电位(mfVEP)和视野检测,采用同一个体的患眼治疗前后与健侧眼及15例(30只眼)正常对照组的比较方法,主要分析多焦视觉诱发电位(mfVEP)的特征,按不同离心度的同心环进行分析,并与视野检测进行比较。结果患眼治疗前与对侧健眼比较:病变受累区域P波潜伏时相对对侧健眼对应区域延迟,振幅下降(P<0.05)。患眼治疗前后对比:患眼病变受累区域P波潜伏时有不同程度的改善,有统计学意义(P<0.05),振幅治疗前后有明显差异(P<0.05),治疗后均恢复正常。治疗后患眼与对侧健眼比较:P波振幅无明显差异(P>0.05);而潜伏时却仍有明显差异(P<0.05),有统计学意义。患眼视野平均敏感度和平均缺损度已接近健侧眼。结论多焦视觉诱发电位(mfVEP)可用于视神经炎的诊断及疗效判定,其在评价局部视神经损伤、追踪视神经损伤恢复情况较视野和传统VEP有明显的优势。
Objective To investigate the wavelet character in the same ring according to the dieffrent eccentricity distribution in the multifocal visual evoked potential of optic neuritis：Tracking the local damage to the optic nerve after outbreak of optic neuritis and the recovery after treatment,so offer the objective way of the early diagnosis,the effects of treatments and the monitor of Prognosis.Methods Carry on the multifocal VEP examination to30 eyes with thirty cases of optic neuritis,and adopt to contrast the sick eyes and the normal eyes in the same patients and the 30 eyes of fifteen normal individuals,mainly analysis the multifocal VEP Second- order kernel response,according to the diffent ring in the same heart,analysing each reaction total wave,carrying on the comparison to each ring.Results Before treatment the sick eyes contrast to the normal eyes in the same Patients,the latencies of P- wavelet were lengthened,and the amplitudes of P- wavelet were lowered（P〈0.05）.Contrast the before treatment of the sick eyes to the after treatment,the latencies of P- wavelet have the improvement of different degree（P〈0.05）,and the amplitudes of P- wavelet have the obvious difference（P〈0.05）,all of the amplitudes recover the normal after treatment.After treatment the sick eyes contrast to the normal eyes in the same patients,the amplitudes of p-wavelet have no obvious difference（P〉0.05）,the latencies of p- wavelet still have the obvious difference（P〈0.05）.Conclusions The multifocal VEP can apply the early diagnosis of optic neuritis,and the effects of treatments,and have the obvious advantage in estimating the local damage to the optic.Nerve and traeking the recovery of damage of the optic nerve contrasting to visual field or the traditional VEP.
出处
《航空航天医学杂志》
2016年第7期805-808,共4页
Journal of Aerospace medicine
关键词
视神经炎
视觉诱发电位
多焦视觉诱发电位
视野
optic neuritis
visual evoked Potential
muliofcal visual evoked Potential
visual field
