摘要
目的探讨医院新生儿重症监护病房(NICU)中导管相关性感染病原菌分布情况,为临床治疗提供理论指导依据。方法回顾性分析2014年6月-2015年6月在医院NICU收治1 051例新生儿,分析导管相关的感染率、病原菌的分布情况,数据采用SPSS 16.0软件进行统计分析。结果 1 051例新生儿发生医院感染102例,感染率为9.71%,其中发生导管相关性血流感染(CRBSI)19例,发生呼吸机相关性肺炎(VAP)9例;CRBSI和VAP发生率随着新生儿出生时体质量的增加而降低,差异有统计学意义(P<0.05);28例新生儿共检出28株病原菌,以革兰阴性杆菌为主,共23株占82.14%。结论医院感染中导管相关性感染多发生于新生儿静脉营养和机械通气,与感染相关的高危因素是新生儿出生时的体质量,导管相关性感染病原菌以克雷伯菌属、铜绿假单胞菌、葡萄球菌属为主,临床上应给予重视。
OBJECTIVE To investigate the distribution of pathogenic bacteria of catheter related infections in the hospital NICU,so as to provide theoretical guidance and basis for clinical treatment.METHODS A total of 1051 cases of children admitted to hospital NICU from Jun.2014 to Jun.2015 were under retrospectively analysis.The catheter-related infection rate and pathogenic bacteria distribution were analyzed.SPSS 16.0was used for statistic analysis.RESULTS There were 102 cases of nosocomial infections in 1051 cases of newborns,and the infection rate was 9.71%,among which 19 cases had catheter-related blood stream infection（CRBSI）and 9cases had ventilator-associated pneumonia（VAP）;CRBSI and VAP incidence rates decreased with the increasing birth weight of newborns,and the difference was significant（P〈0.05）.A total of 28 strains of pathogenic bacteria were isolated from the 28 cases of newborns,mainly gram-negative bacteria,totally 23 strains,accounting for 82.14%.CONCLUSION Most of the catheter-related infections happens because of intravenous nutrition to the children and mechanical ventilation,and the risk factor associated with infections is birth weight.The main pathogens related to catheter are Klebsiella,Pseudomonas aeruginosaand Staphylococcus,which should be given attention in clinic.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3450-3451,3469,共3页
Chinese Journal of Nosocomiology
基金
福建省卫生厅医学科研基金资助项目(2011-2-72)
关键词
新生儿重症监护病房
导管相关性感染
病原菌
流行病学调查
Neonatal intensive care unit
Catheter-related infection
Pathogens
Epidemiological investigation
