摘要
目的研究干扰素辅助治疗反复呼吸道感染患儿疗效及其对免疫功能的影响程度,以达到有效控制反复呼吸道感染。方法选取2014年6月-2015年7月于医院进行治疗60例反复呼吸道感染患儿为研究对象,随机分为对照组30例和观察组30例,对照组进行常规治疗,观察组则在对照组的基础上加用干扰素,比较两组患儿治疗总有效率,数据采用SPSS 17.0软件进行统计分析。结果观察组患儿治疗总有效率为93.33%,显著高于对照组73.33%;治疗后1、2、3个疗程外周血T、B淋巴细胞亚群与红细胞免疫指标均好于对照组,以上指标比较,差异均有统计学意义(P<0.05)。结论干扰素辅助治疗反复呼吸道感染患儿的疗效较好,对于患儿免疫功能的调节作用也较为突出。
OBJECTIVE To study the effect of interferon adjuvant therapy in children with recurrent respiratory tract infection and influence degree on the immune function of children,in order to achieve the goal of controlling the recurrent respiratory tract infection.METHODS A total of 60 cases of children with recurrent respiratory tract infection in our hospital from Jun.2014 to Jul.2015 were selected,and randomly divided into control group and observation group,with 30 cases in each group.The patients in control group were treated with conventional treatment of recurrent respiratory tract infection,and in observation group were treated with interferon based on the conventional treatment,then the total effective rates of the two groups were compared.RESULTS The total effective rate of observation group was 93.33%,which was significantly higher than 73.33% of control group;the eripheral blood T,B lymphocyte subsets and erythrocyte immune indexes at first,second and third course after the treatment were all better than those of control group,and the differences were all significant（P〈0.05）.CONCLUSIONThe effect of interferon adjuvant therapy in children with recurrent respiratory tract infection are better,and its regulating effect for the immune function of children are prominent.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3557-3558,3561,共3页
Chinese Journal of Nosocomiology
基金
河南省中青年卫生科技创新人才基金资助项目(201209878X)
关键词
干扰素
反复呼吸道感染
患儿
临床疗效
免疫功能
Interferon
Recurrent respiratory tract infection
Children
Clinical effect
Immune function
