期刊文献+

希罗达单药治疗复发转移乳腺癌的近期疗效和不良反应 被引量:2

下载PDF
导出
摘要 目的观察希罗达单药治疗复发转移乳腺癌的近期疗效和不良反应。方法选取我院2014年1月~2015年12月收治的复发转移乳腺癌患者38例作为研究对象,采用单药希罗达进行治疗,治疗后,比较患者的疗效及不良反应。结果治疗1周期后,临床获益率为78.9%,治疗结束后,临床获益效为92.1%,治疗结束后临床获益率高于治疗1周期;治疗期间,出现不良反应17例(44.7%)。结论对复发转移乳腺癌患者采取希罗达进行治疗,疗效明显,不良反应症状较轻,患者耐受度好,具有临床推广价值。
作者 王莉 胥科辉
出处 《实用妇科内分泌电子杂志》 2016年第8期113-113,115,共2页 Electronic Journal of Practical Gynecological Endocrinology
  • 相关文献

参考文献5

二级参考文献33

  • 1[1]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2):485
  • 2[2]Talbot DC, Moiseyenko V, Van Belle S, et al. Randomised,phase Ⅱ trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreatedwith anthracyclines. Br J Cancer, 2002, 86 (9):1367
  • 3[3]Meta-analysis goup in cancer. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced coleorectal cancer. J Clin Oneol. 1998, 16:301
  • 4[4]Meta-analysis group in carcer. Toxicity of fiuorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors. J Clin Oncol, 1998, 16:3537
  • 5[5]Lokich JJ, Moore C. Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome. Ann Inter Med, 1984, 101 :798
  • 6[6]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2) :485
  • 7[7]Vukelja SJ, Lombardo FA, James WD, et al. Pyridoxine for the palar-plantar erythrodysesthesia syndrome. Ann Inter Med,1989, 111:688
  • 8[8]Fabian CJ, Molina R, Slavik M, et al. Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. Invest New Drugs, 1990, 8:57
  • 9[9]Jucgla A, Sais G. Hand-foot syndrome. J Clin Oncol, 1997, 15: 3164
  • 10[10]Mortimer JE, Anderson I. Weekly fluorouracil and high-dose leucovorin: Efficacy and treatment of cutaneous toxicity. Cancer Chemother Pharmacol, 1990, 26:449

共引文献172

同被引文献9

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部