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颈动脉粥样硬化不同狭窄程度与冠心病发生率的相关性 被引量:13

Correlation among different degrees of carotid atherosclerotic stenosis and incidence rate of coronary heart disease
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摘要 目的:探讨不同颈动脉粥样硬化狭窄程度与冠心病发生率及严重程度的相关性。方法:选择我院行冠脉造影的患者199例,根据颈动脉彩超结果,患者被分为内膜增厚组(51例)、软斑块组(42例)、硬斑块组(67例)和混合斑块组(39例),计算比较各组Crouse积分,Gensini评分和冠心病发病率。分析Crouse积分与Gensini评分的相关性。结果:与内膜增厚组比较,软斑块组、硬斑块组和混合斑块组的冠心病发病率(19.6%比73.8%比53.7%比74.4%)均显著升高(P均<0.01),且软斑块组和混合斑块组的显著高于硬斑块组(P均<0.05)。与软斑块组和硬斑块组比较,混合斑块组Crouse积分[(4.57±0.72)分比(4.36±0.54)分比(5.09±0.80)分]显著升高,P<0.05或<0.01。与内膜增厚组比较,软斑块组、硬斑块组和混合斑块组的Gensini评分[(15.12±4.33)分比(35.11±5.17)分比(32.55±3.08)分比(40.43±4.21)分]均显著升高,且软斑块组和混合斑块组的显著高于硬斑块组,混合斑块组的显著高于软斑块组的,P<0.05或<0.01。Pearson相关分析显示,斑块组的Crouse积分与Gensini评分呈显著正相关(r=0.646,P=0.005)。结论:颈动脉彩超对冠心病有一定的预测价值,值得临床推广应用。 Objective:To explore the correlation among different degrees of carotid atherosclerotic stenosis and incidence rate and severity of coronary heart disease(CHD).Methods:A total of 199 patients undergoing coronary angiography in our hospital were involved.According to results of carotid color ultrasound,patients were divided into intima thickening group(n=51),soft plaque group(n=42),hard plaque group(n=67)and mixed plaque group(n=39),Crouse score and Gensini score were calculated and compared,incidence rate of CHD was compared among all groups.The correlation between Crouse score and Gensini score was analyzed.Results:Compared with intima thickening group,there were significant rise in incidence rate of CHD(19.6% vs.73.8% vs.53.7% vs.74.4%)in soft plaque group,hard plaque group and mixed plaque group(P〈0.01all),and those of soft plaque group and mixed plaque group were significantly higher than that of hard plaque group(P〈0.05both).Compared with soft plaque group and hard plaque group,there was significant rise in Crouse score[(4.57±0.72)scores vs.(4.36±0.54)scores vs.(5.09±0.80)scores]in mixed plaque group,P〈0.05or0.01.Compared with intima thickening group,there was significant rise in Gensini score[(15.12±4.33)scores vs.(35.11±5.17)scores vs.(32.55±3.08)scores vs.(40.43±4.21)scores]in soft plaque group,hard plaque group and mixed plaque group,those of soft plaque group and mixed plaque group were significantly higher than that of hard plaque group,and that of mixed plaque group was significantly higher than that of soft plaque group,P〈0.05or0.01.Pearson correlation analysis indicated that Crouse score was significant positively correlated with Gensini score in plaque group(r=0.646,P=0.005).Conclusion:Carotid color ultrasound possesses certain predictive value for CHD,which is worth extending.
作者 苏布道
出处 《心血管康复医学杂志》 CAS 2016年第4期390-393,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 颈动脉疾病 冠心病 超声检查 多普勒 彩色 Carotid artery diseases Coronary disease Ultrasonography doppler color
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