摘要
目的探讨乳腺手术预防性使用抗菌药物与乳腺术后伤口感染关系,为合理应用抗菌药物提供参考依据。方法选择2013年1月-2015年6月医院收治非感染性乳腺手术患者200例,随机分为观察组与对照组各100例,对照组术前给予抗菌药物预防切口感染,观察组术前未给予抗菌药物,比较两组患者围手术期切口感染率、术后体温及白细胞计数情况,数据采用SPSS 19.0软件进行统计分析。结果观察组围手术期切口感染率为2.0%,对照组为1.0%,差异均无统计学意义;两组患者术后体温、WBC计数围手术期各时间段比较差异无统计学意义;观察组住院时间、住院费用分别为(7.75±1.25)d、(10263.5±138.25)元,对照组为(7.25±1.5)d、(11358±162.56)元,两组比较住院费用差异有统计学意义(P<0.05)。结论乳腺手术预防性使用抗菌药物与乳腺术后切口感染无关,是一种不合理应用抗菌药物的措施,且增加了患者住院费用。
OBJECTIVE To investigate the relationship between prophylactic use of antibiotics and postoperative wound infections in breast surgery,so as to provide the basis for rational use of antibiotics.METHODS A total of200 cases of non-infected breast surgery patients in the hospital from Jan.2013 to Jun.2015 were selected and randomly divided into observation group and control group,with 100 cases in each group.Control group were treated with antibiotics to prevent infection while observation group were not given antibiotics.The wound infection rates,postoperative temperature,and white blood cell count of the two groups were compared,and the data were analyzed by SPSS 19.0.RESULTS The infection rate was 2%in observation group,and was 1%in control groups,and the difference was not significant.The postoperative body temperature and WBC count of the two groups were not significant.The hospital time and the hospital cost of observation group were（7.75±1.25）d and（10263.5±138.25）yuan,which were significantly lower than（1.5 ±7.25）d,（11358±162.56）yuan of control group（P〈0.05）.CONCLUSIONThe prophylactic use of antibiotics in breast surgery has no relationship with the postoperative wound infections,and it will increase the cost of hospitalization.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第16期3763-3765,共3页
Chinese Journal of Nosocomiology
基金
海南省卫生厅基金资助项目(琼卫2011-73)
关键词
乳腺手术
抗菌药物
切口感染
Breast surgery
Antibiotics
Wound infection
