摘要
目的研究先天性心脏病（congenitalheartdisease，CHD）在早产儿中的发病率及短期预后。方法回顾性收集广东省人民医院2009年1月至2013年12月收治的胎龄〈37周，且生后确诊存在除动脉导管未闭或房间隔缺损外的CHD早产儿资料。参考美国VON（VermontOxfordNetwork）的定义将CHD分类。收集所有患儿的一般情况、手术情况及短期预后。结果总共1406例早产儿中，48例（3．4％）存在CHD，严重CHD有25例（52．1％）。CHD早产儿胎龄为（33．1±2．7）周，出生体质量为（1828±614）g，男30例（62．5％），住院时间为18（10～42）d，出院时纠正胎龄为38（36～41）周。33例（68．8％）无需新生儿期手术。接受手术患儿的手术日龄为20（14～33）d，手术时纠正胎龄为38（36—39）周，手术时体质量为（2237±241）g。出院时宫外生长发育迟缓的发生率为65．9％。结论早产儿CHD发病率和病死率高，生后宫外生长发育迟缓比例高。过半数患儿无需手术或在新生儿期内无需手术。
Objectives To determine the incidence of congenital heart disease （CHD） in preterm infants and the short- term outcomes. Methods The clinical data of preterrn infants hospitalized in Guangdong General Hospital from January 2009 to December 2013 were retrospectively reviewed. These preterm infants were diagnosed as CHD [except patent？ ductus arteriosus （PDA） or atrial septal defect] with gestational age less than 37 weeks. Diagnosis was classified based on the definition of CHD in Vermont Oxford Network. General information, surgery information and short-term outcomes of these infants were collected. Results Among 1 406 preterm infants documented, 48 （3.4%） infants were diagnosed as CHD including 25 cases （52.1% ） with severe CHD. The gestational age of these infants was （33.1 ±2.7） weeks, birth weight was （1828±614） g. Thirty cases （62.5%） were male. Duration of stay in hospital was 18 （10-42） days. Postmenstrual age （PMA） at discharge was 38 （36-41） weeks. For infants receiving surgery, age at surgery was 20 （14-33） days, PMA at surgery was 38 （36-39） weeks, weight at surgery was （2 237±241 ） g. Extrauterine growth retardation （EUGR） happened in 65.9% infants. Conclusions Incidence and mortality rate of CHD in preterm infants are high, with a high rate of EUGR. Surgical treatment in the first month is not necessarily in more than half of these infants.
出处
《岭南心血管病杂志》
2016年第4期437-441,共5页
South China Journal of Cardiovascular Diseases
基金
国家"十二五"科技支撑计划项目(项目编号:2011BA111B227)
关键词
先天性心脏病
早产儿
发病率
预后
congenital heart disease
preterm infants
incidence
outcome
