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术中极化液对腹部恶性肿瘤手术患者胰岛素抵抗的疗效

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摘要 目的对腹部恶性肿瘤手术患者术中进行极化液治疗,观察极化液对患者术后胰岛素抵抗的治疗作用。方法将40例腹部恶性肿瘤患者,随机分为观察组和对照组,观察组麻醉后即给予极化液治疗,对照组仅给予常规输液,检测麻醉前,术后第1、3、7天患者空腹血糖,胰岛素以及细胞因子C反应蛋白(CRP)和肿瘤坏死因子-α(TNF-α)的水平,采用稳态模式评估法HOMA计算患者的胰岛素抵抗指数(HOMA-IR)。结果与对照组相比,观察组细胞因子TNF-α和CRP表达水平降低,胰岛素抵抗程度有所改善,两者差异有统计学意义(P>0.05)。结论对腹部恶性肿瘤患者术中给予极化液治疗能够改善患者的胰岛素抵抗状态,有利于患者的预后。
出处 《广东医学》 CAS 北大核心 2016年第15期2338-2339,共2页 Guangdong Medical Journal
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