摘要
目的探讨认知行为治疗对恢复期精神分裂症患者精神症状及执行功能的影响。方法将80例恢复期精神分裂症患者随机分为研究组(药物治疗合并认知行为治疗)和对照组(单用药物治疗)。于入组时及治疗后第3、12个月末采用阳性和阴性综合征量表(PANSS)、威斯康星卡片分类测验(WCST)进行评定。结果治疗后第3个月末,研究组PANSS总分、阴性症状分、一般精神病理分均较入组时降低(P<0.05);治疗后第12个月末,两组PANSS总分及各因子分较入组时降低(P<0.05)。治疗后第3个月末,研究组PANSS总分、一般精神病理分低于对照组(P<0.05);治疗后第12个月末,研究组PANSS总分、阳性症状分及一般精神病理分均低于对照组(P<0.05)。治疗后第12个月末,研究组WCST总测验数、持续错误数、随机错误数均较入组时降低(P<0.05);正确应答数、分类数均较入组时升高(P<0.05)。治疗后第12个月末,研究组WCST总测验数、持续错误数、随机错误数均低于对照组(P<0.05);正确应答数、分类数均高于对照组(P<0.05)。结论认知行为治疗能有效改善恢复期精神分裂症患者的精神症状及执行功能。
Objective To explore the effect of Cognitive Behavior Therapy on psychiatric symptom and executive function in schizophrenic patients in rehabilitation stage. Methods 80 patients with schizophrenia in rehabilitation stage were randomly divided into study group treated with antipsychoties combined with CBT and control group treated with antipsyehotics only. They were assessed with the Positive and Negative Syndrome Scale （PANSS） and Wisconsion Card Sorting Test （WCST） at baseline and the end of the 3nd, 12th month. Results At the end of the 3nd month, the total score and factor scores of negative symptoms and general psychopathology in PANSS in study group decreased significantly compared with the baseline （P 〈 0. 05 ）. At the end of the 12th month, the total score and all factor scores of PANSS in both groups decreased significantly compared with the baseline （P 〈0.05）. At the end of the 3rd month, the total score and factor score of general psychopathology of PANSS in study group were lower than those in control group （P 〈 0.05 ） ;and at the end of the 12th month, the total score and factor scores of positive symptoms and general psychopathology in study group were lower than those in control group（ P 〈 0.05 ）. At the end of the 12th month, the total test numbers, perseverative errors and random errors of WCST in study group all decreased significantly compared with the baseline（P 〈 0.05） ; and the correct responses, categories completed all increased significantly compared with the baseline （P 〈 0.05 ）. At the end of the 12th month, the total test numbers, perseverative errors and random errors of WCST in study group were all less than those in control group（P 〈 0.05 ） ; and the correct responses, categories completed were more than those in control group （P 〈 0.05）. Conclusion CBT can improve symptoms and executive function in schizophrenic patients in rehabilitation stage.
出处
《精神医学杂志》
2016年第3期193-195,共3页
Journal of Psychiatry
关键词
认知行为治疗
精神分裂症
恢复期
执行功能
Cognitive Behavior Therapy Schizophrenia Rehabilitation stage Executive function
