摘要
目的观察电针和普芦卡必利治疗功能性便秘的临床疗效。方法将40例患者随机分成两组,每组20例,治疗组用电针治疗,对照组口服普芦卡必利,观察两组患者主要症状评分、粪便性状评分及血清P物质(Substance P,SP)和生长抑素(Somotostatin,SS)含量的变化。结果两组患者治疗前后排便频率及排便费劲得分差值比较差异均无统计学意义(P>0.05),排便不尽感、腹痛和粪便性状得分差值比较差异有统计学意义(P<0.05);两组治疗后血清SP及SS与同组治疗前比较差异均有统计学意义(P<0.05);治疗组总有效率为90.0%,对照组总有效率为85.0%,两组疗效比较差异无统计学意义(P>0.05)。结论电针和普芦卡必利治疗功能性便秘疗效相当,在改善患者症状方面各有优势,临床应根据患者具体病情合理选择。
Objective To observe the clinical efficacies of electroacupuncture and Prucalopride succinate tablets in treating functional constipation.Method Forty patients were randomized into two groups,20 cases in each group.The treatment group was intervened by electroacupuncture,and the control group was by oral administration of Prucalopride succinate tablets.The major symptoms scores,stool shape score,serum substance P（SP）,and somotostatin（SS） were observed.Result After treatment,there were no significant inter-group differences in comparing the changes of defecation frequency and difficulty scores（P〈0.05）,while there were significant inter-group differences in comparing the changes of incomplete bowel evacuation sensation,abdominal pain,and stool shape scores（P〈0.05）;the serum SP and SS levels were significantly changed after treatment in both groups（P〈0.05）;the total effective rate was 90.0% in the treatment group versus 85.0% in the control group,and the difference was statistically insignificant（P〈0.05）.Conclusion Electroacupuncture and Prucalopride succinate tablets can produce equivalent efficacies in treating functional constipation,and have their own advantages in improving the relevant symptoms.Therefore,treatment should be chosen according to the disease condition.
出处
《上海针灸杂志》
2016年第8期926-929,共4页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家"十二五"科技支撑计划项目(2012BAI24B01)
关键词
便秘
电针
CCS评分
Bristol评分
Constipation
Electroacupuncture
Cleveland Clinic Score
Bristol Score
