摘要
目的比较单纯经皮椎体成形术（PVP）和内固定联合PVP治疗脊柱转移癌的疗效。方法将43例脊柱转移癌患者按治疗方法分为两组,分别采用PVP及内固定联合PVP治疗。术后7 d及术后12个月时采用疼痛视觉模拟评分（VAS）和Oswestry功能障碍指数（ODI）进行疗效比较。结果患者均获得随访,时间24-59个月。术后7 d及术后12个月VAS：PVP组分别为2.70-3.90（3.39±0.44）分、2.00-3.40（2.73±0.57）分,内固定联合PVP组分别为2.60-4.00（3.39±0.54）分、2.10-3.50（2.83±0.56）分;术后7 d及术后12个月时ODI：PVP组分别为19.00-25.50（22.54±2.17）分、24.10-25.67（25.37±0.15）分,内固定联合PVP组分别为19.11-25.52（25.54±2.17）分、22.12-24.42（23.37±0.13）分。两项指标两组比较差异均有统计学意义（P〈0.05）,内固定联合PVP组优于PVP组。术后PVP组l例肿瘤复发,内固定联合PVP组2例肿瘤复发,两组比较差异无统计学意义（P〉0.05）。结论对脊柱转移癌,尤其是多节段转移患者内固定联合PVP较单纯PVP能更加有效地缓解疼痛,恢复脊柱稳定,提高生活质量。
Objective To compare the therapeutic effect of percutaneous vertebroplasty（ PVP） alone and percutaneous pedicle instrumentation combined with PVP for metastatic spine tumors. Methods Forty-three patients with metastatic spine tumors were divided into two groups： PVP alone as group 1 and percutaneous pedicle instrumentation combined with PVP as group 2. Postoperation 7 d,12 months,visual analogue scales（ VAS）,Oswestry disability index（ ODI） of two methods were compared respectively. Results All patients were followed up for 24 - 59 months.Preoperation and postoperation 7 d,12 months,VAS were 2. 70 - 3. 90（ 3. 39 ± 0. 44）,2. 00 - 3. 40（ 2. 73 ± 0. 57）points in group 1,and 2. 60 - 4. 00（ 3. 39 ± 0. 54）,2. 10 - 3. 50（ 2. 83 ± 0. 56） points in group 2. ODI： 19. 00 -25. 50（ 22. 54 ± 2. 17）,24. 10 - 25. 67（ 25. 37 ± 0. 15） points in group 1,and 19. 11 - 25. 52（ 25. 54 ± 2. 17）,22. 12 - 24. 42（ 23. 37 ± 0. 13） points in group 2. There were significant differences between two groups（ P〈0. 05）,and group 2 was better than group 1. Vertebral tumor recurrence occurred in 1 patient,and 2 patients in group 2.There were no significant differences between two groups（ P〈0. 05）. Conclusions For multiple segmental metastatic spine tumors,compared with PVP alone,percutaneous pedicle instrumentation combined with PVP is more effective in correcting deformity,relieving pain,maintaining vertebral height and restoring spinal stability.
出处
《临床骨科杂志》
2016年第4期415-418,共4页
Journal of Clinical Orthopaedics
关键词
经皮椎体成形术
脊柱肿瘤
转移癌
percutaneous vertebroplasty
spine neoplasms
metastatic tumors
