摘要
目的了解辽宁省调整碘盐浓度后碘缺乏病防治效果,评估持续消除碘缺乏病进展。方法按人口比例概率抽样法抽取30个抽样县（市、区）,单纯随机抽样方法在抽样县抽取l所小学,每个小学抽取50名8～10岁儿童,检查甲状腺容积,采集尿样和食用盐样品,检测尿碘和盐碘。在小学所在乡（镇、街道）抽取20名孕妇采集尿样和盐样,检测尿碘和盐碘。结果 1520名儿童食用盐含碘量23.9mg/kg,碘盐覆盖率为98.9%（1503/1520）,合格碘盐食用率94.3%（1433/1520,25±30%）,甲状腺肿大率1.8%（28/1520）,儿童尿碘中位数159.1μg/L,达到了国家碘缺乏病消除标准且儿童尿碘水平适宜。621名孕妇食用盐含碘量23.5mg/kg,碘盐覆盖率为98.1%（609/621）,合格碘盐食用率78.6%（488/621,30±30%）,尿碘中位数131.5μg/L,尿碘低于孕妇适宜碘营养水平的下限（150μg/L）。食用含碘量24-36mg/kg（30±20%）碘盐孕妇的尿碘中位数为147.4μg/L,更接近碘营养适宜水平;食用含碘量27-33mg/kg（30±10%）碘盐孕妇的尿碘中位数为167.5μg/L,达到碘营养适宜水平,且低尿碘孕妇比例显著降低。结论辽宁省碘缺乏病综合防治措施实施成效显著,省级水平保持了消除碘缺乏病状态。供应加碘量25mg/kg和30 mg/kg的2个浓度碘盐设计合理,满足不同人群的碘营养需求,符合因地制宜、分类指导、科学补碘的碘缺乏病防治原则。建议适当降低食用盐含碘量的允许变异范围。
Objectives To understand current situation of prevention and control of iodine deficiency disorders（ IDD） after adjusting the amount of iodized salt,and to evaluate the progress in eliminating IDD in Liaoning province of China.Methods 30 counties were sampled based on the sampling method of Probability Proportional to Size.A primary school was chosen in each county by the randomized sampling method,50 students of 8 to 10 years old in each school were sampled for examining their thyroid volume,and tested their urinary iodine level and household salt iodine level.Near the location of these primary schools chosen20 pregnant women in each township were sampled to test their urinary iodine level and salt iodine level.Results 1 520children＇s goiter rate was 1.8%,which was obviously lower than the IDD elimination standard at the national level（ 5%）;the iodizedsalt coverage rate was 98.9% and the consumption rate of qualified iodized salt was 94.3%.All figures had achieved the national standard.The mean of salt iodize content of 1 520 children was 23.9 mg / kg;the MUI of children was 159.1 μg / L.Urinary iodine of children was at adequate level.The mean of iodine content in the edible salt of 621 pregnant women is 23.5mg / kg（ 21～ 39 mg / kg）,The rate of qualified iodized salt 78.6%（ 488 /621）,median urinary iodine was 131.5 μg / L,The level of iodine nutrition of pregnant women was lower than the optimum level limit（ 150 μg / L）.The pregnant women edible iodized salt 24 ～ 36 mg / kg of iodine content,the median urinary iodine were 147.4 μg / L;The iodine content of edible iodized salt 27 ～ 33 mg / kg of pregnant women,the median urinary iodine 167.5 μg / L,reached the appropriate levels of iodine nutrition,and pregnant women of low urinary iodine significantly reduced.Conclusions Control measures implemented with remarkable results of IDD in Liaoning province,IDD has been eliminated at the provincial level.25 mg / kg or 30 mg / kg of iodine concentration iodized salt in design of supply reasonable to meet the needs of different groups for scientific iodine supplementation.
出处
《中国地方病防治》
CAS
北大核心
2016年第5期481-484,共4页
Chinese Journal of Control of Endemic Diseases
基金
2014年国家重大公共卫生专项资金地方病防治项目
关键词
碘缺乏
儿童
孕妇
尿
食用盐
流行病学研究
Iodine deficiency disorders
Children
Pregnant women
Urine
Edile Salt
Epidemic studies
