摘要
目的研究贫血患者血细胞形态学及血常规特点。方法选择2013年8月至2015年8月商洛市中心医院收治的贫血患者63例为观察组,另选取同期在本院进行健康的体检的62例人群为对照组。对所有研究对象进行血细胞形态学检查,记录所有研究对象的血细胞形态学检查结果、血细胞形态异常阳性、周围血常规情况。结果小细胞低色素性贫血组平均红细胞血红蛋白浓度(MCHC)、平均红细胞体积(MCV)、血细胞比容(HCT)均显著低于正常细胞性贫血组[(293±11)g/L比(347±6)g/L、(72.34±2.82)f L比(88.27±3.32)f L、(24.52±0.96)%比(43.63±1.64)%](P<0.05),红细胞体积分布宽度(RDW-CV)显著高于正常细胞性贫血组[(23.4±0.9)%比(14.8±0.6)%](P<0.05)。单纯小细胞性贫血组MCV、HCT[(71.99±2.77)f L、(25.63±0.99)%]显著低于正常细胞性贫血组(P<0.05),MCHC、RDW-CV[(348±13)g/L、(14.9±0.6)%]与正常细胞性贫血组比较差异无统计学意义(P>0.05)。大细胞性贫血组MCHC、RDWCV、MCV、HCT[(441±26)g/L、(23.1±1.4)%、(134.65±8.08)f L、(91.22±5.47)%],均高于正常细胞性贫血组(P<0.05)。观察组患者的血小板、血红蛋白、中性粒细胞百分比、白细胞数量低于对照组[(231±11)×109/L比(281±15)×109/L、(122±5)g/L比(141±3)g/L、(0.48±0.06)比(0.63±0.05),(4.2±1.1)×109/L比(7.1±2.1)×109/L],观察组患者的淋巴细胞百分比显著高于对照组[(0.49±0.04)比(0.40±0.03)],差异有统计学意义(P<0.01)。结论在贫血患者中有着较高的MCHC、RDW-SD、MCV、HCT、淋巴细胞数量,存在较低的血小板、血红蛋白、中性粒细胞、白细胞数量。
Objective To study the blood cell morphology and routine blood test characteristics in anemia patients. Methods Total of 63 patients with anemia in Shangluo City Central Hospital from Aug. 2013 to Aug. 2015 were included as an observation group, another 62 eases for health examination during the same period were included as a control group. They were compared with the results of morphological examination of blood cells, positive abnormal shape of blood cells, and routine peripheral blood test. Results Small cell hypochromic anemia group mean corpuscular hemoglobin concentration（MCHC） ,mean cell volume（MCV） , hematoerit （HCT） were significantly lower than normal cell anemia group [ （293 ± 11 ） g/L vs （347 ± 6 ） g/L, （72. 34 ± 2. 82 ） fL vs （ 88. 27 ± 3.32 ） fL, （24. 52 ± 0. 96 ） % vs （43.63 ± 1.64 ） % ] （ P 〈 0. 05 ）, red Blood Cell Volume Distribution Width- coefficient of variation（RDW-CV） was,higher than the normal cell anemia group [ （23.4 ± 0. 9 ） % vs （ 14. 8 ± 0. 6 ） % ] （ P 〈 0. 05 ）. Simple small-cell anemia group MCV, HCT were （71.99 ± 2. 77 ） %, （25.63 ± 0. 99 ） %, which were lower than the normal cell anemia group （ P 〈 0. 05 ） , MCHC, RDW-CV respectively were （348 ± 13 ） g/L, （ 14. 9 ± 0. 6 ） % , and there was no significant difference compared with normal cell anemia group （ P 〉 0.05 ）. Large cell anemia group MCHC, RDW-CV, MCV,HCT were （441 ±26） g/L,（23.1 ±1.4）%,（134.65 ±8.08） fL,（91.22 ±5.47）% respectively, which were all higher than normal cell anemia group（ P 〈 0.05 ）. The platelet, hemoglobin, neutrophils per- centage,and leukocytes number were lower than the control greup [（231 ± 11）×10^9/L vs （281 ± 15）×10^9/L,（122±5） g/L vs （141 ±3） g/L,（0.48 ±0.06） vs （0.63 ±0.05）,（4.2 ±1.1） ×10^9/L vs （7.1 ±2. 1 ）×10^9/L]. The lymphocytes percentage of the observation group was significantly higher than the control group [（ 0. 49 ± 0.04 ） vs （0. 40 ± 0. 03 ） ], the differences were statistically significant （ P 〈 0. 01 ）. Conclusion Patients with anemia have higher MCHC, RDW-SD, MCV, HCT, lymphocyte number, lower platelet, hemoglobin, neutrophils, and white blood cell counts.
出处
《医学综述》
2016年第17期3488-3490,共3页
Medical Recapitulate
关键词
贫血
血细胞形态学
血常规
Anemia
Blood cell morphology
Routine blood test
