摘要
目的研究舒利迭吸入剂联合复方血栓通胶囊对稳定期慢性阻塞性肺疾病(COPD)老年患者血栓前状态的影响。方法将2011年2月至2014年12月期间院内收治的老年稳定期COPD患者80例纳入本次研究,并将其随机分为研究组和对照组,每组40例,对照组患者采用舒利迭吸入剂50μg/500μg,每次1吸,2次/d;研究组在对照组的治疗基础上加用复方血栓通胶囊,3次/d,每次1.2 g,疗程持续1月。分别在治疗前后检测2组患者血浆纤维蛋白原(FIB)、D-二聚体(D-D)、总同型半胱氨酸(THCY)以及血气指标,进行对比分析。结果与治疗前比较,2组治疗后FIB、D-D、THCY下降,动脉血氧分压(PaO_2)增加,动脉血二氧化碳分压(PaCO_2)下降,差异均有统计学意义(P<0.05);2组间比较,差异亦有统计学意义(P<0.05)。结论采用舒利迭吸入剂联合复方血栓通胶囊可以显著改善稳定期COPD老年患者血栓前状态,改善患者缺氧和二氧化碳潴留情况。
Objective To explore the effect of seretide inhalation combined with compound xueshuantong capsule on thrombosis in the elderly patients with stable chronic obstructive pulmonary disease （COPD）. Methods Eighty elderly patients with stable COPD from December 2014 to February 2011 were enrolled in this study and randomly divided into study group and control group, with 40 cases in each group. The control group was treated with seretide inhaler, with dose of 50 μg/500 μg, two times a day. The study group received compound blood stasis capsule additionally on the basis of control group, 3 times a day, each time 1.2 g, for 1 month. The levels of blood fibrinogen （FIB） , D-Dimer （ D-D）, total homocysteine （THCY） , and blood gas index before and after the treatment in two groups were detected and compared. Results The levels of FIB, THCY, D-D, and PaCO2 were decreased, and the level of PaO2 was increased （P〈0.05） in two groups,especially in the study group （P〈 0.05）. Conclusions Using seretide inhalation combined with compound xueshuantong capsule plays a stabilizing role in improving prethrombotic state in elderly COPD patients in stable stage, and can effectively improve hypoxia and carbon dioxide retention.
出处
《实用老年医学》
CAS
2016年第8期651-653,共3页
Practical Geriatrics
关键词
复方血栓通胶囊
舒利迭吸入剂
慢性阻塞性肺疾病
稳定期
compound xueshuantong capsule
seretide inhalation
chronic obstructive pulmonary disease
stable stage
