摘要
目的探讨自发性低颅压(SIH)的发病机制、临床特点、影像学表现和预后转归。方法分析北京协和医院近20年间12例SIH患者的临床和影像学表现,进行长期随访,了解其预后转归。结果12例患者均为成年起病,表现为体位性头痛,经保守对症治疗后症状好转。SIH头颅MRI显示脑叶出血、硬膜下血肿、小脑扁桃体下位、蛛网膜下腔出血、脑室变小、垂体充血、脑静脉窦扩张、弥漫性硬脑膜强化。结论SIH以体位性头痛为特点,其MRI改变与脑脊液容量减少后发生的代偿改变有关,远期预后较好。
Objective To investigate the pathogenesis, clinical presentation, imaging features and prognosis of spontaneous intracranial hypotension. Methods Clinical manifestation and imaging changes of 12 patients with spontaneous intraeranial hypotension were reported. They were followed up regularly. The clinical and neuroimaging characteristics were summarized. Results All the 12 eases were adults, presenting with orthostatic headache. They all recovered with conservative therapy. Head MRI demonstrated cerebral lobe hemorrhage, subdural hematoma, pituitary hyperemia, subarachnoid hemorrhage, enhancement of the pachymeninges, sagging of the brain, etc. Conclusions Spontaneous intracranial hypotension is characterized by orthostatie headaches and is associated with compensatory changes following loss of CSF volume. The long-time prognosis is not bad.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2016年第33期2625-2628,共4页
National Medical Journal of China
关键词
自发性低颅压
体位性头痛
低颅压
头痛
Spontaneous intracranial hypotension
Orthostatic headache
Intracranial hypotension
Headache