摘要
目的研究探讨熊去氧胆酸联合枸橼酸莫沙必利治疗胆汁反流性胃炎的临床疗效。方法选取2015年01月至2016年03月于我站诊治的84例胆汁反流性胃炎患者,随机分为观察组与对照组,对照组单纯予以枸橼酸莫沙必利片治疗,观察组在予以枸橼酸莫沙必利片的基础上联合运用熊去氧胆酸治疗,观察与比较两组患者的恶心、呕吐、腹痛、腹胀等症状改善情况及治疗有效率等临床疗效。结果与对照组相比,观察组患者的临床治疗有效率明显高于对照组,其差异具有统计学意义(P<0.05);观察组患者治疗后的恶心、呕吐、腹痛、腹胀等症状评分显著低于对照组,其差异具有统计学意义(P<0.05)。结论在胆汁反流性胃炎的治疗中,联合运用熊去氧胆酸联合枸橼酸莫沙必利更能有效改善患者的临床症状,提高治疗有效率,进而改善预后,值得临床上进一步应用推广。
Objective To study the clinical efficacy of Ursodesoxycholic Acid and Mosapride Citrate in the treatment of BRG. Methods 84 BRG patients treated from January 2015 to March 2016 in our hospital were se- lected. The subjects were randomly divided into two groups. The control group took Mosapride Citrate; the ob- servation group took Mosapride Citrate and Ursodesoxycholic Acid. The symptoms of nausea, vomiting, stom- achache and abdominal distension as well as the effective rate for two groups was compared. Results The clinical effective rate of observation group was higher than that of control group （P 〈 0.05） ; the evaluation score of nau- sea, vomiting, stomachache and abdominal distension for observation group was significantly lower than that of control group（P 〈 0.05）. Conclusion For BRG patients, Ursodesoxycholic Acid and Mosapride Citrate can ef- ficiently improve the clinical symptoms, effective rate and prognosis. It is worthy of further application and pro- motion.
出处
《内蒙古医学杂志》
2016年第4期432-434,共3页
Inner Mongolia Medical Journal
