摘要
目的观察射干合剂治疗小儿咳嗽的临床疗效。方法将285例咳嗽患儿随机分为治疗A组、治疗B组及对照组,每组90例。在常规治疗的基础上,治疗A组加用射干合剂、治疗B组加用宣肺止嗽合剂、对照组加用氨溴特罗口服液治疗。各组疗程均为7天,观察临床疗效及中医证候的变化情况。结果 1试验期间,各组共脱落15例,脱落率5.26%(<10%);最终完成试验者270例,每组90例。2治疗A组、治疗B组及对照组临床总有效率分别为91.11%、80.00%和77.78%;组间临床疗效比较,差异有统计学意义,治疗A组明显优于治疗B组、对照组(P<0.05)。3治疗前后组内比较,各组中医证候积分差异均有统计学意义(P<0.05)。组间治疗后总体比较,中医证候积分差异有统计学意义(P<0.05);其中治疗A组中医证候积分减分差值显著大于治疗B组、对照组(P<0.05);治疗B组与对照组中医证候积分减分差值差异无统计学意义(P>0.05)。结论射干合剂治疗小儿咳嗽的疗效满意,可显著缓解患儿的临床症状。
Objective To observe the clinical effect of Shegan mixture in the treatment of infantile cough. Methods 285 children with cough were randomly divided into the treatment group A, treatment group B and control group, 90 cases in each group. Based on conventional therapy, the treatment group A was treated with Shegan mixture, treatment group B were treated with Xuanfei Zhike mixture, while the control group was treated with oral lipid of ambrocol, additionally, with a course of 7 days. The clinical effects and the changes of TCM syndromes were observed. Results ①15 cases were dropped totally and the expulsion rate was 5. 26% （ 〈 10% ）during the experiment. Finally, 270 cases were finished, 90 cases in each group.②The clinical total effective rate of the treatment group A, treatment group B and control group was 91. 11%, 80% and 77.78%, respectively. The difference of clinical curative effect between groups was statistically significant, the effect in the treatment group A was significantly better than that in the treatment group B and control group（ P 〈 0.05 ）. ③Compared within group before and after treatment, the difference of TCM syndrome score in each group was statistically significant （ P 〈 0.05 ）. Compared between groups after treatment, the difference of TCM syndrome score was statistically significant （ P 〈 0.05 ） ; among, the reduction of TCM syndrome score in the treatment group A was significantly lower than that in the treatment group B and the control group （ P 〈 0.05 ） ; there was no significant difference on the reduction of TCM syndrome score between the treatment group B and control group （ P 〉 0.05 ）. Conclusion The curative effect of Shegan mixture in the treatment of infantile cough was significant, which obviously alleviated the clinical symptoms.
出处
《上海中医药杂志》
2016年第9期48-51,共4页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市科委中医重点项目(13401902700)
关键词
小儿咳嗽
射干合剂
阳性药物对照
射干麻黄汤
infantile cough
Shegan mixture
positive control drug
Shegan Mahuang Decoction
