期刊文献+

血管性认知障碍早期诊断的研究进展 被引量:7

Progress on Early Diagnosis of Vascular Cognitive Impairment
下载PDF
导出
摘要 目的血管性认知障碍(VCI)涵盖从轻度认知障碍到痴呆全过程,近年来其发病率逐年增高,且痴呆患者由于严重的认知功能障碍而丧失了治疗机会,严重影响患者的生活质量,因此,早期诊断VCI具有重要的临床意义。本文介绍了临床评估、神经影像学检查、神经心理评估、生物学标志物等在VCI早期诊断中的应用价值,以期为早期诊断VCI提供参考。 Vascular cognitive impairment(VCI)rangs from mild cognitive impairment to dementia,and its morbidity increases obviously in recent years. Due to severe cognitive dsyfunction,dementia patients lose the opportunity for treatment, which badly affect the quality of life,so early diagnosis of VCI is of great clinical significance. This paper reviewed the application of clinical assessment,neurological imaging examination,neuropsychological assessment and biomarkers in the early diagnosis of VCI,in order to provide references for clinicians.
出处 《实用心脑肺血管病杂志》 2016年第8期5-8,共4页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 认知障碍 诊断 神经成像 神经心理学 生物学标志物 Cognition disorders Diagnosis Neuroimaging Neuropsychiatry Biomarker
  • 相关文献

参考文献25

  • 1BARBA R,MARTNEZ-ESPINOSA S,RODRGUEZ-GARCíA E,et al.Poststroke dementia:clinical features and risk factors[J].Stroke,2000,31(7):1494-1501.
  • 2贾建平,魏翠柏.血管性认知障碍提出的临床意义[J].中华老年医学杂志,2005,24(1):9-11. 被引量:41
  • 3GORELICK P B,COUNTS S E,NYENHUIS D.Vascular cognitive impairment and dementia[J].Biochim Biophys Acta,2016,1862(5):860-868.
  • 4HACHINSKI V,IADECOLA C,PETERSEN R C,et al.National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards[J].Stroke,2006,37(9):2220-2241.
  • 5VERNOOIJ M W,IKRAM M A,VROOMAN H A,et al.White matter microstructural integrity and cognitive function in a general elderly population[J].Arch Gen Psychiatry,2009,66(5):545-553.
  • 6O'SULLIVAN M.Imaging small vessel disease:lesion topography,networks,and cognitive deficits investigated with MRI[J].Stroke,2010,41(10 Suppl):S154-158.
  • 7WANG S,YUAN J,GUO X,et al.Neurochemical correlates of cognitive dysfunction in patients with leukoaraiosis:a proton magnetic resonance spectroscopy study.[J].Neurol Res,2012,34(10):989-997.
  • 8GASPAROVIC C,PRESTOPNIK J,THOMPSON J,et al.1H-MR spectroscopy metabolite levels correlate with executive function in vascular cognitive impairment[J].J Neurol Neurosurg Psychiatry,2013,84(7):715-721.
  • 9STEEL R M,BASTIN M E,MCCONNELL S,et al.Diffusion tensor imaging(DTI)and proton magnetic resonance spectroscopy(1H MRS)in schizophrenic subjects and normal controls[J].Psychiatry Res,2001,106(3):161-170.
  • 10CHEN S Q,CAI Q,SHEN Y Y,et al.Hydrogen Proton Magnetic Resonance Spectroscopy in Multidomain Amnestic Mild Cognitive Impairment and Vascular Cognitive Impairment Without Dementia[J].Am J Alzheimers Dis Other Demen,2016,31(5):422-429.

共引文献40

同被引文献86

引证文献7

二级引证文献54

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部