摘要
目的：观察眼底荧光素血管造影（FFA）在糖尿病视网膜病变（DR）患者中的应用效果。方法回顾分析85例（161只眼）DR 患者的临床资料，所有患者均进行 FFA 检查，分析 DR 各期分布情况及毛细血管无灌注区（NP）分布情况，探讨糖尿病性黄斑病变（DM）与 DR 各期的关系。结果DR 各期分布特征Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ期比例分别为14．29％、44．72％、34．78％、3．11％、3．11％。161只眼视网膜病变共出现 NP 69只眼，NP 在视网膜不同象限的分布差异有统计学意义（χ2＝13．931，P ＜0．01），以鼻侧出现 NP 的发生率最高，达81．16％；NP 在距视盘不同距离视网膜上的分布差异有统计学意义（χ2＝68．017，P ＜0.01），以中周部出现 NP 的发生率最高，达84．06％。Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ期黄斑病变的发生率分别为8．70％、31．94％、58．93％、80.00％、80．00％。DM分期和 DR 有相关性（χ2＝26．093，P ＜0．01）。结论FFA 可为 DR 严重程度分级和DM改变情况提供依据，DM的发生率、严重程度与 DR 分级呈正相关，视网膜中周部及鼻侧象限是 NP 好发及常见发生的部位。
Objective To observe the effect of fundus fluorescein angiography（FFA）for diabetic retinopathy （DR）.Methods FFA results of 85 cases（161 eyes）were retrospectively analyzed.The distribution of DR,the dis-tribution of non -perfusion （NP）,the relationship between diabetic maculopathy （DM）and different DR period were studied.Results The ratios of Ⅰ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ of DR were 14.29%,44.72%,34.78%,3.11%,3.11%.NP was found in 69 eyes in 161 DR eyes.The occurrence of NP was highest （81.26%）in nasal,there was NP difference in the distribution of the different quadrants （χ2 =13.931,P 〈0.01）,there were NP differences at different distances from the optic disc.The occurrence of NP was highest （84.06%）in midperiphera.The incidence rates of macular degeneration in Ⅰ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ of DR were 8.70%,31.94%,58.93%,80.00%,80.00%.There was correla-tion between DMand DR （χ2 =26.093,P 〈0.01）.Conclusion FFA can provid information for DR severity grad-ing and DM,there were positively correlations between incidence and severity of DM and DR grade,NP was usually occurred at the nasal retina and the midpefipheral retina.
出处
《中国基层医药》
CAS
2016年第18期2818-2821,共4页
Chinese Journal of Primary Medicine and Pharmacy
