摘要
在生命科学研究蓬勃发展的后基因组学时代,系统生物学已成为研究复杂生命现象的重要手段和研究热点。以高通量组学技术为技术平台,研究特定生理状态下大量基因、蛋白质或代谢产物等生物大分子的表达模式变化规律,有助于建立与生物表型变化的相关性,为探究生理过程的分子调节机制提供依据。本文总结了广泛应用的多种组学的研究进展,同时对该技术在蜜蜂领域的研究加以综述,为蜜蜂系统生物学研究提供重要参考资料。
High-throughput studies of biological systems are rapidly accumulating a wealth of ＇omics＇-scale data which have allowed researchers to better assess the complexity and diversity of the system biology in the post-genome era. Omics-based applications such as genome, transcriptome and proteome have been performed in various bioscientific researches for the integrated visualizations that give biological insight into the profiles of abundant of gene, protein and metabolite etc, well benefit the construction of the relationship between the traits and biomacromolecule as well as the molecular regulation mechanism of certain physiological processes. The current understanding and processing of widely used omics-based applications are summarized in this review, also with emphasis on its performance and achievement in honeybee research.
出处
《中国蜂业》
2016年第9期15-19,共5页
Apiculture of China
基金
国家自然科学基金项目(No.31572470)
山东省农业良种工程项目"优质高产蜜蜂及蚕桑新品种培育"(2014-2016)
国家蜂产业技术体系建设专项资金(No.CARS-45)
