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克罗恩病肠壁纤维化机制的研究进展 被引量:5

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摘要 克罗恩病(CD)的肠道炎性反应可累及肠壁全层,病变肠壁的纤维化更易发生肠腔狭窄,甚至肠梗阻及肠瘘,其发生机制尚未完全明确。近年来国内外的研究显示,CD肠壁纤维化的发生可能与细胞外基质(ECM)的降解失衡、细胞及其产生的细胞因子、敏感基因、氧化应激、肠道菌群等因素有关。此文就近年来CD肠壁纤维化机制的研究进展作一综述。
出处 《国际消化病杂志》 CAS 2016年第1期22-24,69,共4页 International Journal of Digestive Diseases
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