摘要
目的:探讨桥本甲状腺炎(HT)超声弹性评分和弹性系数与甲状腺自身免疫功能的相关性。方法:216例桥本甲状腺炎患者,采用GE LOGIQ3型彩色多普勒超声诊断仪获得满意弹性图像后,评定弹性评分及弹性系数;化学发光法检测甲状腺功能及甲状腺过氧化物酶抗体(TPOAb)、甲状腺球蛋白抗体(Tg Ab)滴度,分别分析甲状腺超声弹性评分和弹性系数与甲状腺自身抗体相关性。结果:216例HT患者血清促甲状腺激素(TSH)、TGA、TPO明显升高,Tg Ab的滴度与弹性系数呈正相关,r=0.54,P<0.01;Tg Ab与弹性评分呈正相关,r=0.496,P<0.01;TPOAb与弹性应变系数呈正相关,r=0.77,P<0.01,TPOAb与弹性评分呈正相关,r=0.73,P<0.01。结论:实时超声弹性成像评分结合甲状腺自身免疫功能检测,有助于提高桥本甲状腺炎诊断的正确性。
Objective： To investigate the correlation between ultrasonic elasticity score,elasticity coefficient and autoimmune thyroid function in patients with HT（ hashimoto thyroiditis）. Methods： Used GE LOGIQ3 type Color Doppler Ultrasound Diagnostic System to acquire satisfactory elastosonography from 216 patients with HT,and evaluated the elasticity score and elasticity coefficient; to detecte the thyroid function and the titer of Thyroid peroxidase antibody（ TPOAb）,Thyroid globulin antibody（ Tg Ab） by chemiluminescence,respectively investigated the correlation between ultrasonic elasticity score,elasticity coefficient and autoimmune thyroid function. Results： Serum Thyroid stimulating hormone（ TSH）,TGA and TPO in 216 patients with HT increased significantly,Tg Ab and elastic coefficient were positively correlated,r = 0. 54,P〈0. 01; Tg Ab and elasticity score were positively correlated,r = 0. 496,P〈0. 01; TPOAb and elastic coefficient were positively correlated,r = 0. 77,P〈0. 01,TPOAb and elasticity score were positively correlated,r = 0. 73,P〈0. 01. Conclusion： Real-time ultrasound elastography in combination with measurement of autoimmune thyroid function was helpful to diagnosis of HT.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2016年第8期1204-1207,1211,共5页
Chinese Journal of Immunology
基金
泰安市科技发展计划(No.201540186)
山东省中医药科技发展计划(No.2015-266)
关键词
桥本甲状腺炎
超声弹性成像
弹性评分
弹性系数
自身免疫
Hashimoto＇s thyroiditis
Ultrasonic elastography
Elastic score
Strain ratio
Autoimmunity
