摘要
目的探讨非小细胞肺癌(non-small cell lung cancer,NSCLC)患者化疗期间抑郁危险因素。方法选取2013年12月至2015年12月于本院接受治疗的NSCLC患者100例为研究对象。调查分析患者的文化程度、个人经济收入及生活习惯等可能影响其心理状态的因素。采用抑郁自评量表(selfrating depression scale,SDS)对患者的抑郁状况进行评分,并比较SDS评分≥50分和<50分的影响因素之间的差异;采用Logistic多因素分析患者发生抑郁的高危因素。结果年龄、病程、肿瘤直径、文化程度、个人经济收入、病情程度、生活习惯、性格特点均是NSCLC患者化疗期间发生抑郁的影响因素(P<0.05)。多因素Logistic回归分析显示:高中以下文化程度、个人经济收入≤2000元/月、恶性肿瘤、性格内向是NSCLC患者化疗期间发生抑郁的高危因素(P<0.05)。结论高中及以上文化水平、个人经济收入≤2000元/月、恶性肿瘤、性格内向是NSCLC患者化疗期间发生抑郁的高危因素。医护人员应关注此类患者化疗期间的情绪变化,及时对其不良情绪进行疏导,保证化疗顺利进行。
Objective To discuss the risk factors of depression in patients with non-small cell lung cancer（NSCLC） during chemotherapy period. Method 100 cases of patients with NSCLC treated in our hospital from December 2013 to December 2015 were selected as the study objects. Education level, personal economic income, habits and customs and other factors which may affect the psychologic status of patients were investigated and analyzed. Self-rating depression scale（SDS） was used to grade the depression of patients, and the difference between the influence factors of SDS score ≥ 50 points and〈 50 points were compared, used multivariate logistic regression analysis to analyze the risk factors of depression in patients. Result Age, course of disease, tumor diameter, cultural standing, personal economic income, pathogenetic condition, habits and customs, character were the influencing factors of depression in patients with NSCLC during chemotherapy period（P〈0.05）, Logistic regression analysis showed that education level lower than senior middle school, personal economic income ≤ 2000 yuan/month, malignant tumor, introversion were the risk factors of depression in patients with NSCLC during chemotherapy period（P〈0.05）. ConclusionEducation level lower than senior middle school, personal economic income ≤ 2000 yuan/month, malignant tumor, introversion are the risk factors of depression in patients with NSCLC during chemotherapy period, health care workers should pay attention to the emotional changes in patients during chemotherapy, to dredge the negative emotion of patients duly, to ensure the progress of chemotherapy.
出处
《中国医学前沿杂志（电子版）》
2016年第8期80-83,共4页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
非小细胞肺癌
化疗
抑郁
危险因素
Non-small cell lung cancer
Chemotherapy
Depression
Risk factor
