摘要
目的:分析变应性鼻炎(AR)伴慢性鼻-鼻窦炎(CRS)鼻息肉患者的变应原种类及血清特异IgE(sIgE)、总IgE强度的特点。方法:收集2015-06-2016-04期间就诊于宁夏医科大学总医院耳鼻咽喉头颈外科的50例AR不伴CRS鼻息肉患者(A组)和50例AR伴CRS鼻息肉的患者(B组),进行血清sIgE和总IgE强度检测并进行分析。结果:A、B组患者病程无差异,接受检测的患者中仅有4例为单一变应原阳性,均为A组患者,B组患者均为混合型变应原阳性。2组的变应原分布特点,吸入类以蒿属类和户尘螨为主,食物类以海鲜和坚果类为主;两者变应原种类有差异,B组患者食物类变应原百分率高于A组(P<0.05),而吸入类低于A组(P<0.05),但sIgE平均强度差异无统计学意义(P>0.05),总IgE强度明显高于A组(P<0.05)。结论:AR伴CRS鼻息肉患者的食物性变应原阳性发生率高,过敏反应较AR不伴CRS鼻息肉患者强度高。
Objective.. To study the influeace of allergen, sIgE,total IgE in allergic rhinitis and chronic rhniosinusitis with nasal polyps. Method.. Fifty patients with allergic rhinitis and fifty patients with both allergic rhinitis and nasal polyp were involved in this study. Average dense of sIgE and total IgE in serum were dectected. The kinds of allergens between the two groups were siginificantly diffierent; there was no siginificantly diffierence on sIgE average dense（P〉0. 05） ;total IgE dense was higher in allergic rhinitis and chronic rhniosinusitis with nasal polyps patients（P〉0.05）. Conclusion..AR with nasal polyps in patients was high proportion of food allergies and allergic reactions strength was high than the AR.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2016年第17期1352-1353,1358,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
宁夏自然科学基金资助(No:NZ15232)
关键词
鼻炎
变应性
变应原
鼻息肉
rhinitis,allergic
allergen
nasal polyps
