摘要
目的:对矮紫堇的化学成分进行研究。方法:采用系统溶剂提取,通过反复硅胶柱色谱、凝胶Sephadex LH-20柱色谱、半制备高效液相色谱等技术进行分离纯化,运用NMR,MS等波谱方法以及结合文献数据对分离得到的化合物进行结构鉴定。结果:从藏族药矮紫堇中分离得到13个化合物,分别鉴定为芹菜素(1),槲皮素(2),木犀草素(3),山柰酚(4),5,7,4’-三羟基二氢黄酮(5),芦丁(6),槲皮苷(7),紫云英苷(8),乌苏酸(9),齐墩果酸(10),豆甾醇(11),β-谷甾醇(12),胡萝卜苷(13)。结论:所有化合物均为首次从该藏族药矮紫堇中分离得到。
Objective： To investigate the chemical constituents of Corydalis hendersonii. Method： The constituents were extracted by using systematic solvents,separated and purified by repeated silica gel column chromatography,Sephadex LH-20 column chromatography,semi-preparative HPLC,etc. The structures of the obtained constituents were identified by using NMR,MS and other spectral methods as well as literature data.Result： Thirteen compounds were obtained and identified as apigenin（ 1）,quercetin（ 2）,luteolin（ 3）,kaempferol（ 4）,5,7,4＇-trihydroxy flavanone（ 5）,rutin（ 6）,quercitrin（ 7）,astragalin（ 8）,ursolic acid（ 9）,oleanic acid（ 10）,stigmasterol（ 11）,β-sitosterol（ 12）,and daucosterol（ 13）. Conclusion： All the components were obtained from Corydalis hendersonii for the first time.
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2016年第18期60-63,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
江西省卫生和计划生育委员会项目(2014A030)
江西中医药大学校级科研课题项目(JXXT201402023)
关键词
矮紫堇
化学成分
黄酮
三萜
甾体
Corydalis hendersonii
chemical constituents
flavones
triterpenoids
steroids
