摘要
目的:探索心脑合病(即冠心病心绞痛合并动脉粥样硬化性血栓性脑梗死)的证候分类及证候特征。方法:采用临床流行病学调查的横断面研究方法,收集2009年5月到2010年7月在我国11家三级甲等医院就诊的982例心脑合病患者的症状、体征、舌象、脉象等中医四诊信息建立数据库,采用频数统计及因子分析、关联规则等数据挖掘方法,对心脑合病的证候进行归纳分析。结果:心脑合病患者出现频率较高的四诊信息依次是:肢体不遂、胸闷、乏力、头晕、身体困重、神疲、少气懒言,胸痛、肢体麻木、舌下脉络紫色等;心脑合病患者证候分为8类:气血亏虚、肝气郁结、痰浊壅盛、脾肾阳虚、痰热内蕴、痰瘀互结、心肾阴虚、气虚血瘀,并初步确定了各证候的诊断要点。结论:心脑合病中医证候可分8型,运用因子分析、关联规则的无监督分析方法研究证候分类及证候特征有一定的科学性、客观性和实用性。
Objective：To explore the syndrome characteristics and classifications of angina pectoris combined with atherosclerotic thrombotic cerebral infarction（XNHB） by using factor analysis combined with association rules.Methods：Totally of 982 patients with XNHB in May 2009 to July 2009 from 11 top three hospitals were selected by using cross-sectional study method of clinical epidemiological investigation.The symptoms,physical signs,tongue-appearances,pulse manifestation and so on of the 982 patients were collected to establish the database of information from the TCM four diagnostic methods.The syndromes of patients with XNHB were summarized and analyzed by using data mining methods as frequency count,factor analysis,association rules,and so on.Results：The information from the TCM four diagnostic methods of patients appeared more frequently were hemiplegia,chest distress,lacking in strengthen,dizzy,heaviness in body,weary,lack of energy,chest pain,black in sublingual venation.The syndromes of XNHB patients could be divided into 8 types such as syndrome of dei ciency of qi and blood,syndrome of stagnation of liver qi,syndrome of exuberance of phlegm,syndrome of yang dei ciency of spleen and kidney,syndrome of phlegm-heat blocking internally,syndrome of intermingled phlegm and blood stasis,syndrome of yin dei ciency of heart and kidney,and syndrome of blood stasis due to dei cient qi,and the diagnosis essentials of each syndromes were determined preliminarily.Conclusion：The TCM syndromes of XNHB can be divided into 8 types,and it has a certain scientific,objective and practical to study syndrome characteristics and classification with unsupervised analysis method as factor analysis and association rules.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2016年第9期3484-3489,共6页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家中医药管理局中医药行业科研专项资助项目(No.200807061)~~
关键词
心脑合病
冠心病心绞痛
动脉粥样硬化性血栓性脑梗死
因子分析
关联规则
证候分类
Angina pectoris combined with atherosclerotic thrombotic cerebral infarction
Angina pectoris
Atherosclerotic thrombotic cerebral infarction
Factor analysis
Association rules
Syndrome classification
