摘要
目的研究血液灌流（HP）联合血液透析（HD）在尿毒症周围神经病变（UPN）治疗中的临床疗效。方法：选取66例UPN患者，随机分为2组，分别给予HP联合HD治疗及单纯HD治疗。比较两组治疗前后临床症状改善情况等。结果：试验组临床症状改善情况明显优于对照组（P〈0．05）；试验组血清BUN、Hcy、PTH、B2-MG、TNF-α、IL-6和CRP水平明显低于对照组（P〈0．05），正中神经、胫神经以及腓总神经SCV明显快于对照组（P〈0．05）。两组KT／V比较，差异无统计学意义（P〉0．05），且均未出现不良反应。结论：血液灌流联合血液透析治疗尿毒症周围神经病变疗效优于单纯血液透析治疗。
Objective To study the effect of hemoperfusion （HP） combined with hemodialysis （HD） in uremic peripheral neuropathy （UPN） therapy in clinical curative effect. Methods： 66 patients with UPN treated in our hospital as the research object, randomly divided into 2 groups, were treated with HP combined with HD treatment and HD treatment alone. Two groups were compared before and after treatment of clinical symptoms to improve the situation. Results： Compared with the control group, experimental group patients clinical symptoms improvement was better than that of the control group （P〈0.05）; experimental group, serum BUN, Hey, PTH, beta 2-mg, TNF-α, IL-6 and CRP levels was significantly lower than that of the control group （P〈0.05）. The test group median and tibial nerve and common peroneal nerve SCV was significantly faster than the control group （P〈0.05）. KT/V were eompared between the two groups, there was no statistically significant difference （P〉0.05）, and there was no adverse reaction. Conclusion： The effect of hemoperfusion and hemodialysis in treatment of uremic peripheral neuropathy is better than hemodialysis treatment.
出处
《世界中医药》
CAS
2016年第B06期1738-1739,共2页
World Chinese Medicine
关键词
血液灌流
血液透析
尿毒症周围神经病变
临床疗效
blood perfusion
hemodialysis
peripheral nerve disease in uremia
clinical effect
