摘要
目的探讨眼部黏膜相关淋巴组织（MALT）淋巴瘤临床病理特征。方法：回顾性分析本院34例眼部MALT淋巴瘤的临床病理资料及免疫表型。结果：肿瘤细胞为分化良好的小B淋巴细胞。肿瘤细胞B细胞表面抗原和bcl—2多弥漫（＋），T细胞表面抗原（-）。CD10、cyclinD1（-），2例CD5（＋）。Ki67较低。结论：MALT淋巴瘤是眼部最常见的淋巴瘤，眼眶发病占首位，其次是眼喻、泪腺、结膜。其临床表现及病理特征不具有特异性，与良性反应性增生等鉴别比较困难。通常需通过光镜、免疫组化等方法进行鉴别。恶性度不高，早诊断早治疗预后较好。
Objective To investigate the clinical pathological features of MALT lymphoma in ocular adnexal tissues. Methods： 34 cases of ocular adnexal MALT lymphoma treated at our hospital were retrospectively analyzed tile clinical pathological data and immune phenotype. Results：Tumor cells were good small lymphocytes.The B cell surface antigen and the BCL-2 of Tumor cells were more diffuse positive（＋）,T cell surface antigen（-）.CD lO,cyclinD 1（-）,CD5（＋）in 2 cases.Ki67 was low. ConclusiomMALT lymphoma is the most common disease in eyes.orbital disease accounted for the first place, followed by eyelids,tear ducts, conjunctiva.Its clinical manifestations and pathological features have no specificity,It is more difficult to identify the benign hypertplasia of reactivity. Usually by light microscopy, immunohistochemistry techniques to identify.Malignant degree is not high,Prognosis is good if early diagnosis and treatment.
出处
《世界中医药》
CAS
2016年第B06期2061-2061,共1页
World Chinese Medicine
