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替格瑞洛治疗不稳定型心绞痛临床疗效及对血清hs—CRP、IL-6、TNF-a水平的影响 被引量:3

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摘要 目的探讨替格瑞洛治疗不稳定型心绞痛的临床疗效及对血清超敏c-反应蛋白(hs—CRP)、白介素-6(IL-6)和肿瘤坏死因子-a(TNF—a)水平的影响。方法:选择不稳定心绞痛患者80例,随机分为研究组(研究组,40例)和对照组(对照组,40例),两组患者均给予常规冠心病治疗,研究组患者口服替格瑞洛,对照组口服氯吡格雷,治疗4周。结果:治疗后研究组治疗总有效率为92.5%,明显高于对照组的75.O%,差异有统计学意义(P〈0.05)。两组患者治疗后血清hs—ERP、IL-6、TNF—a水平均较治疗前均明显下降(P〈0.05),且研究组明显低于对照组(P〈0.05)。结论:与氯吡格雷比较,替格瑞洛更能改善不稳定型心绞痛患者临床症状,具有更强抗血小板和抗炎作用。
出处 《世界中医药》 CAS 2016年第B03期615-615,共1页 World Chinese Medicine
基金 国家自然科学基金资助项目(N0:30971242)
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