摘要
目的:采用系统评价方法,评估针灸治疗肠易激综合征的临床有效性和安全性。方法:计算机检索CNKI、CBM、VIP和WF相关文献,制定严格的纳入排除标准,数据采用Cochrane协作网提供的Revmans 5.3进行统计分析。结果:纳入18篇RCT,共1210例,多数纳入试验质量不高。Meta分析显示:(1)针灸与西药比较,治愈率RR=1.56,95%CI[1.17,2.08],Z=3.02,P<0.05,差异有统计学意义;总有效率。纳入8篇RCT,Meta分析显示两组总有效率RR=1.28,95%CI[1.16,1.41],Z=4.86,P<0.05,差异有统计学意义;症状积分的WMD=-3.02,95%CI[-3.40,-2.63],Z=15.29,P<0.05,差异有统计学意义。(2)针灸+中药与西药比较,治愈率RR=1.61,95%CI[0.98,2.66],Z=1.88,P>0.05,差异无统计学意义;总有效率RR=1.18,95%CI[1.05,1.33],Z=2.81,P<0.05,差异有统计学意义;症状积分的WMD=-4.89,95%CI[-5.93,-3.85],Z=9.2,P<0.05,差异有统计学意义。结论:针灸治疗IBS的临床疗效肯定,优于西药治疗。
Objective ：To assess the efficacy and safety of acupuncture treatment of Irritable Bowel Syndrome. Methods： Randomized controlled trials （RCTs） involving acupuncture treatment of Irritable Bowel Syndrome were identified from CBM （ 1978 to 2015）, VIP （ 1989 to 2015 ）, Wanfang Database （ 1998 to 2015 ）, CNKI （ 1979 to 2015）. And some relevant journals were handsearched. The Cochrane Collaboration~ Rev Man 5.3 software was used for meta - analyses. Results： A total of 18 trials involving 1210 patients were included. The result of meta - analyses showed that： （ 1 ） com- pared with western medicine, acupuncture cure rate RR = 1.56, 95% CI （1.17, 2.08 1, Z = 3.02, P 〈 0.05, the difference was statistically significant. The total effective rate. Into 8 RCT, Meta analysis showed that two group total effec- tive rate RR = 1.28, 95% CI （ 1.16, 1.41 ）, Z = 4. 86, P 〈 0.05, the difference was statistically significant; Symptoms integral WMD = 3.02, 95% CI （3.40, 2.63 ）, Z = 15.29, P 〈 0. 05, the difference was statistically significant. （2） compared with western medicine, acupuncture and moxibustion plus Chinese medicine cure rate RR = 1.61, 95% CI （0. 98, 2.66 ~, Z = 1.88, P 〉 0.05, there was no statistically significant difference; Total effective rate RR = 1.18, 95% CI （1.05, 1.33）, Z = 2. 81, P 〈 0.05, the difference was statistically significant;Symptoms integral WMD = 4. 89, 95% CI （5.93, 3.85）, Z =9.2, P 〈0.05, the difference was statistically significant. Collusion： the clinical curative effect of acupuncture better than western medicine in the treatment of IBS.
出处
《中华中医药学刊》
CAS
北大核心
2016年第9期2171-2174,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家重点基础研究发展计划(973计划)项目(2015CB554503)
国家自然科学基金项目(81202854)
江西中医药大学校级项目(2014ZR031)
关键词
针灸
肠易激综合症
系统评价
acupuncture and m oxibustion
irritable bow el syndrome
Systematic Review
