摘要
目的探讨竹叶石膏汤加减配方对围术期输血患者免疫功能的影响.方法选取 140例外科手术围术期输血患者,随机将他们分为观察组和对照组,每组各 70例,观察组患者给予竹叶石膏汤加减口服处理,对照组患者不服用竹叶石膏汤,检测两组患者淋巴细胞亚群中CD3＋、CD8＋、CD4＋及NK细胞数量.计算CD4＋/CD8＋值.通过ELISA法检测两组患者血清中sIL-2R、IL-6的浓度水平.结果观察组患者的CD3＋、CD4＋、NK细胞数量及CD4＋/CD8＋显著高于对照组,而CD8＋数量明显低于对照组.对照组患者血清中的sIL-2R、IL-6的浓度水平与观察组患者相比明显增加.结论围术期输血患者的免疫功能受到很大抑制,应用竹叶石膏汤可有效减轻输血带来的免疫抑制作用,从而提高患者的免疫作用,有重要的临床推广和应用价值.
objectiveto study the bamboo leaves gypsum soup reduction formula on the immune function of patients with perioperative blood transfusion. Methodschoose 140 cases of surgical perioperative blood transfusion patients, they are randomly divided into observation group and control group, 70 cases in each group and observation group patients give bamboo leaves gypsum soup oral treatment, control group patients not taking bamboo leaves gypsum soup, detection of two groups of patients in the lymphocyte subsets CD3 ＋, CD8 ＋, CD4 ＋ and NK cells. Calculation of CD4 ＋ / CD8 ＋ value. By ELISA method to detect the two groups patients serum sIL - 2 r and IL - 6 levels. Resultsthe observation group of patients on the number of CD3 ＋, CD4 ＋ and NK cells and CD4 ＋ / CD8 ＋ is significantly higher than the control group, and the number of CD8 ＋ significantly lower than the control group. In the control group patients serum sIL - 2 r and IL - 6 levels increased significantly compared with observation group of patients. Conclusionthe immune function of patients with perioperative blood transfusion was greatly suppressed, application of bamboo leaves gypsum soup can effectively reduce the immunosuppressive effect from a blood transfusion, thus improve the patient’s immune function, have important clinical popularization and application value.
出处
《湖南中医药大学学报》
CAS
2016年第A01期355-356,共2页
Journal of Hunan University of Chinese Medicine
关键词
围术期输血
竹叶石膏汤加减
免疫功能
perioperative blood transfusion
Bamboo leaves gypsum soup decreases
The immune function
