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阿托伐他汀钙片调酯治疗对急性冠脉综合征患者单核细胞比例、CD54的影响

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摘要 目的研究阿托伐他汀钙片调酯治疗对急性冠脉综合证患者单核细胞比例、CD54的影响.方法 2014 年1 月 -2015 年1 月间,选取我院救治的 81 例急性冠脉综合证患者作为观察组,另选取81健康志愿者作为对照组,观察组给予阿托伐他汀钙片调酯治疗,在治疗前、后(3个月)抽取2组静脉血,测定血脂、ox-LDL、hs-CRP、单核细胞比例、CD54阳性表达率,并进行比较.结果治疗前观察组 TC、LDL-C、HDL-C 与对照组比较,(P〉0.05)差异不显著.治疗后观察组TC、LDL-C 明显下降,组内、组间比较,(P〈0.05)差异显著;治疗前观察组ox-LDL、hs-CRP、单核细胞比例、CD54阳性表达率明显高于对照组,(P〈0.05)差异显著.治疗后观察组ox-LDL、hs-CRP、单核细胞比例、CD54阳性表达率明显下降,与对照组比较,(P〉0.05)差异不显著.结论对急性冠脉综合征患者应用阿托伐他汀钙片调酯治疗,可有效调节血脂、单核细胞比例,抑制炎症反应,值得推广应用.
作者 王准
出处 《湖南中医药大学学报》 CAS 2016年第A01期489-489,共1页 Journal of Hunan University of Chinese Medicine
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