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RECK、TFF2、ERβ在老年患者子宫内膜癌中的表达与预后转归的关联分析 被引量:4

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摘要 目的探讨老年子宫内膜癌患者RECK、TFF2、ERβ的表达及其对疾病的预后作用。方法收集40例老年子宫内膜癌患者的术后标本(癌症组)与20例正常子宫内膜组织标本(对照组),通过免疫组化检测RECK、TFF2、ERβ的蛋白表达。结果癌症组RECK、TFF2、ERβ的阳性表达率分别为42.5%、47.5%和40.0%,均显著低于对照组(75.0%、80.0%和80.0%)(P<0.05)癌症组组织中RECK、TFF2阳性表达与临床病理分期、组织学分级、淋巴结转移和肿瘤复发密切相关(P<0.05);ERβ的表达与组织学分级和淋巴结转移密切相关(P<0.05),而与临床分期及肿瘤复发无相关性。结论 RECK、TFF2和ERβ在老年子宫内膜癌患者中表达各异,与老年子宫内膜癌的发生、发展密切相关,RECK和TFF2对老年子宫内膜癌预后评估具有参考意义。
出处 《中国妇产科临床杂志》 CSCD 北大核心 2016年第5期440-441,共2页 Chinese Journal of Clinical Obstetrics and Gynecology
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