IKZF1基因多态性与中国儿童急性淋巴细胞白血病的相关性
Association of IKZFI gene polymorphism with acute lymphoblastic leukemia in Chinese children
摘要
急性淋巴细胞白血病(ALL)是儿童发病率最高的白血病类型,好发于2-5岁。目前ALL的发病机制仍未明确,但以往研究大多认为其受遗传因子及环境影响。IKZF1(Ikarosfamilyzincfinger1)基因位于染色体7p12.2,其编码蛋白IKAROS是和淋系发育相关的重要转录因子。
出处
《中华血液学杂志》
CAS
CSCD
北大核心
2016年第9期826-828,共3页
Chinese Journal of Hematology
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