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新生儿脑损伤相关因素分析 被引量:12

Analysis on related factors of neonatal brain damage
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摘要 目的 对临床上可能造成新生儿脑损伤的常见因素进行比较分析。方法 回顾性分析该院2011年9月-2014年12月新生儿552例,其中正常产儿276例设为非脑损伤组,脑损伤患儿276例设为脑损伤组,对其孕周、体重、母亲年龄、生产方式等一系列数据进行统计分析。结果 脑损伤组新生儿出生时体重往往过小,低体重儿发生脑损伤的概率明显高于正常体重儿;孕周〈34周分娩的早产儿发生脑损伤的几率明显大于孕周34~40周的新生儿,差异有统计学意义(P〈0.05);多胎妊娠时出现脑损伤情况明显高于单胎妊娠时,差异有统计学意义(P=0.000)。结论 孕周和新生儿体重是新生儿脑损伤的危险因素,孕周和体重越小新生儿患病的危险性越高,尤其是体重〈1 500 g的新生儿,且孕周〈34周的新生儿更容易患病。 Objective To compare and analyze the common causes of neonatal brain damage. Methods A total of 552 neonates se- lected from the hospital from September 2011 to December 2014 were analyzed retrospectively, then they were divided into non-brain damage group (276 neonates) and brain damage group (276 neonates) . The gestational age, weights, maternal age, delivery modes in the two groups were analyzed statistically. Results The birth weight of neonates in brain damage group was usually small, the probability of brain damage in low weight neonates was significantly higher than that in normal weight neonates ; the incidence rate of brain damage in premature infants ( 〈34 gestational weeks) was statistically significantly higher than that in neonates of 34-40 gestational weeks ( P〈0.05 ) ; the inci- dence rate of brain damage in cases of multiple pregnancy was statistically significantly higher than that in cases of single pregnancy (P = 0. 000) . Conclusion Gestational week and neonatal birth weight are risk factors of neonatal brain damage, the lower gestational week and neonatal birth weight are, the higher risk of neonatal diseases is, especially among the neonates with weight〈1 500 g and gestational week〈 34 week, neonatal diseases easily occur among them.
出处 《中国妇幼保健》 CAS 2016年第18期3763-3765,共3页 Maternal and Child Health Care of China
基金 吴阶平医学基金临床科研专项资助基金课题(320.6750.14171) 广西医疗卫生适宜技术研究与开发课题(S201405-03)
关键词 新生儿脑损伤 孕周 体重 早产儿 Neonatal brain damage Gestational week Weight Premature infant
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