摘要
目的调查心胸外科住院患者抗菌药物临床应用情况,制定心胸外科抗菌药物临床应用规范和抗菌药物临床应用差异化指标,为临床医师合理用药提供依据。方法回顾性随机调查我院2014年1-12月心胸外科300例住院患者病历,制定该院心胸外科常见疾病抗菌药物临床应用规范;分析、计算、统计抽样患者抗菌药物使用强度、使用率及Ⅰ类切口预防用抗菌药物使用率的实际值与理论值,确立差异化指标。结果我院2014年心胸外科住院患者实际抗菌药物使用率、Ⅰ类切口预防用抗菌药物使用率和抗菌药物使用强度分别为72.7%、92.6%和61.2DDDs/(100人·d),制定的差异化指标分别为69.3%、63.0%和49.3DDDs/(100人·d)。结论我院心胸外科住院患者抗菌药物临床应用存在无指征用药、用药品种和档次过高、给药疗程过长、联合用药或更换药物不合理等问题,需待加强管理,以促进抗菌药物临床合理应用。
Objective To formulate the clinical application specification of antibiotics ,make a deference index of antibac-terial drugs in chest department according to the investigation about the antibiotics′utility situation in chest department in 2014 and provide a theoretic foundation for the clinical doctor to promote the clinical rational drug use .Methods The antibiotics′ap-plication information of 300 cases inpatients in the chest department of a hospital in 2014 were researched and analyzed through retrospection ,regarding with the relevant regulations and related clinical practice guidelines ,the clinical application specifica-tion of antibiotics was formulated and the analysis ,calculation ,statistics to the actual and theoretical value of the rate and inten-sity of antibiotics′application ,the application rate of the prophylactic antibiotics of type I incision on the inpatients in the chest department had been done .The differentiation index of them were establish .Results The rates of the actual antibiotics′appli-cation and the prophylactic antibiotics of type I incision respectively were 72 .7% and 92 .6% ,while the intensity of antibiotics′application was 61.2 DDDs/（100 persons · d ） . The deference indexes of them were developed 69 .3% , 63 .0% and 49.3 DDDs/（100 persons · d） .Conclusions There′re still much irrational places in the use of antibiotics in chest department of the hospital .It′s essential to strengthen supervision in order to promote the rational use of antibiotics in clinical practice .
出处
《药学实践杂志》
CAS
2016年第5期469-473,共5页
Journal of Pharmaceutical Practice
关键词
抗菌药物
临床应用规范
差异化指标
心胸外科
anti-bacterial drug
the clinical application specification
differentiation index
chest depart
